Department of Clinical Sciences, Swedish University of Agricultural Sciences, P.O. Box 7054, 75007, Uppsala, Sweden.
Sci Rep. 2021 May 5;11(1):9546. doi: 10.1038/s41598-021-88876-3.
Cruciate ligament rupture (CLR) is a common orthopedic disorder in dogs. The study objectives were to evaluate incidence rate (IR), cause-specific mortality rate (CSMR) and risk factors for CLR in insured dogs. A single cohort study of dogs insured in Agria Pet Insurance in Sweden (2011-2016) was performed. Age at diagnosis, IR, CSMR and relative risk (RR) for CLR was calculated overall and per breed. The cohort included just over 600,000 dogs. The IR of CLR was 23.8 (95% confidence interval, 23.1-24.6) cases per 10,000 DYAR. The breeds with highest RR of CLR were Boerboel and Dogo Canario, while the breeds with lowest RR were Standard Dachshund and Miniature Pinscher. Dogue de Bordeaux had highest RR of euthanasia due to CLR. The median age at veterinary care claim for CLR was 7.1 (range 0.3-16.0) years and 6.6 (0.3-12) years at life insurance settlement. Large and giant breeds were generally diagnosed and euthanized due to CLR at a younger age compared to smaller breeds. The majority of the breeds with increased RR of CLR diagnosis and CLR-related euthanasia were large or giant. A pattern of increasing size and decreasing age at diagnosis/CLR-related euthanasia was observed.
十字韧带断裂（CLR）是犬类常见的骨科疾病。本研究旨在评估在瑞典 Agria 宠物保险投保犬的发病率（IR）、特定病因死亡率（CSMR）和 CLR 的相关风险因素。本研究对在瑞典 Agria 宠物保险投保的犬（2011-2016 年）进行了一项单队列研究。计算了总发病率、特定病因死亡率和每一种品种的相对风险（RR）。该队列包括了超过 60 万只犬。CLR 的发病率为 23.8（95%置信区间，23.1-24.6）/10000 犬年。发病率最高的品种为波尔多獒犬和巴西非勒犬，发病率最低的品种为标准雪纳瑞犬和迷你雪纳瑞犬。由于 CLR 而接受安乐死的犬中，杜高犬的相对风险最高。兽医护理索赔中 CLR 的中位年龄为 7.1 岁（范围 0.3-16.0 岁），在人寿保险理赔中为 6.6 岁（范围 0.3-12 岁）。与小型犬相比，大型和巨型犬通常会更早地因 CLR 被诊断并实施安乐死。诊断出的 CLR 风险增加的犬种和与 CLR 相关的安乐死犬种，大多数是大型或巨型犬。诊断/与 CLR 相关的安乐死的犬种的大小和年龄呈增加趋势。
