School of Public Health, Fujian Medical University, Fujian Province, People's Republic China.
Nutr Cancer. 2012;64(4):508-14. doi: 10.1080/01635581.2012.668743. Epub 2012 Apr 10.
After decades of increase, lung cancer has become the leading cause of cancer death among women. The mortality rate from lung cancer is ascending at a relatively steady rate, which has greatly affected the health of the female population and become a serious issue. A case-control study of 226 female lung cancer cases and 269 controls was conducted from 2006 to 2010 in Fujian Province. A structured questionnaire was used to gather information on demographic characteristics as well as dietary and environmental factors. Odds ratios and 95% confidence intervals were estimated by using univariate logistic regression. Multivariate unconditional logistic regression analysis was applied to evaluate the potential interactions of variables or confounders. The consumption of fruit, eggs, and tea was inversely associated with the risk of lung cancer. As expected, cooking oil fumes and environmental tobacco exposure were positively associated with elevated risk. In addition, frequent physical activity and late age at menarche were identified as protective factors of female lung cancer. The results demonstrate that some environmental and dietary factors are related to the risk of lung cancer among the female population in southeast China.
经过几十年的增长,肺癌已成为女性癌症死亡的主要原因。肺癌的死亡率以相对稳定的速度上升,这极大地影响了女性群体的健康,成为一个严重的问题。2006 年至 2010 年,在福建省对 226 例女性肺癌病例和 269 例对照进行了病例对照研究。使用结构化问卷收集人口统计学特征以及饮食和环境因素的信息。使用单因素逻辑回归估计比值比和 95%置信区间。应用多因素非条件逻辑回归分析评估变量或混杂因素的潜在相互作用。水果、鸡蛋和茶的消费与肺癌风险呈负相关。正如预期的那样,烹调油烟和环境烟草暴露与风险升高呈正相关。此外,经常进行体育活动和初潮年龄较晚被确定为女性肺癌的保护因素。研究结果表明,一些环境和饮食因素与中国东南部女性人群的肺癌风险有关。