Rose G, Day S
Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine.
BMJ. 1990 Nov 3;301(6759):1031-4. doi: 10.1136/bmj.301.6759.1031.
To examine the relation between the prevalence of deviation and the mean for the whole population in characteristics such as blood pressure and consumption of alcohol.
Re-examination of standardised data from the Intersalt study, an international, multicentre study on the determinants of blood pressure.
Samples of adults representing 52 populations in 32 countries.
The relations, expressed as correlation coefficients, between the mean population values for blood pressure, body mass index, alcohol consumption, and sodium intake and the prevalence of, respectively, hypertension (greater than or equal to 140 mm Hg), obesity (body mass index greater than or equal to 30 kg/m2), high alcohol intake (greater than or equal to 300 ml/week), and high sodium intake (greater than or equal to 250 mmol/day).
There were close and independent associations between the population mean and the prevalence of deviance for each of the variables examined: correlation coefficients were 0.85 for blood pressure, 0.94 for body mass index, 0.97 for alcohol intake, and 0.78 for sodium intake.
These findings imply that distributions of health related characteristics move up and down as a whole: the frequency of "cases" can be understood only in the context of a population's characteristics. The population thus carries a collective responsibility for its own health and well being, including that of its deviants.
研究血压和酒精摄入量等特征方面的偏差患病率与总体均值之间的关系。
对INTERSALT研究的标准化数据进行重新分析,该研究是一项关于血压决定因素的国际多中心研究。
来自32个国家52个人群的成年人样本。
血压、体重指数、酒精摄入量和钠摄入量的总体均值与高血压(大于或等于140 mmHg)、肥胖(体重指数大于或等于30 kg/m²)、高酒精摄入量(大于或等于300 ml/周)和高钠摄入量(大于或等于250 mmol/天)患病率之间的关系,以相关系数表示。
在所研究的每个变量中,总体均值与偏差患病率之间存在密切且独立的关联:血压的相关系数为0.85,体重指数为0.94,酒精摄入量为0.97,钠摄入量为0.78。
这些发现表明,与健康相关的特征分布整体上会上下变动:“病例”的频率只能在人群特征的背景下理解。因此,人群对自身的健康和福祉负有集体责任,包括对偏离者的健康和福祉。