State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu, P.R. China.
J Dent Res. 2012 Jun;91(6):580-5. doi: 10.1177/0022034512444446. Epub 2012 Apr 4.
The objective of this study was to evaluate the efficacy of cognitive behavioral therapy intervention for patients who experienced pain during orthodontic treatment. The baseline characteristics were assessed via questionnaires and oral examinations. Four hundred and fifty eligible individuals were recruited and randomized by computer-generated block randomization into three groups: cognitive behavioral therapy intervention (n = 150), ibuprofen intervention (n = 150), and no intervention (control; n = 150). Primary outcomes were the change from baseline in pain intensity measured with 100-mm Visual Analog Scale (VAS) scores at 1, 2, 3, 7, 14, and 30 days after initial archwire placement. Outcomes assessment was blinded and followed the intention-to-treat principle. One hundred forty-three (95.30%), 145 (96.70%), and 141 (94.00%) individuals in the cognitive behavioral therapy, the ibuprofen, and the control groups, respectively, completed the one-month follow-up evaluations. Those in the cognitive behavioral therapy group showed a greater decrease in mean VAS scores than did those in the control group over the previous five time-points (p < 0.001). Cognitive behavioral therapy was shown to be effective in pain control during the initial stage of orthodontic treatment. The study registration number was ChiCTR-TRC-00000556.
本研究旨在评估认知行为疗法干预对正畸治疗中出现疼痛的患者的疗效。通过问卷调查和口腔检查评估基线特征。招募了 450 名符合条件的个体，并通过计算机生成的区组随机化将其随机分为三组：认知行为疗法干预组（n = 150）、布洛芬干预组（n = 150）和无干预（对照组；n = 150）。主要结局是在初始弓丝放置后 1、2、3、7、14 和 30 天，使用 100mm 视觉模拟量表（VAS）评分测量的疼痛强度从基线的变化。结果评估是盲法的，并遵循意向治疗原则。分别有 143（95.30%）、145（96.70%）和 141（94.00%）名认知行为疗法、布洛芬和对照组的参与者完成了一个月的随访评估。与对照组相比，认知行为疗法组在前五个时间点的平均 VAS 评分下降幅度更大（p < 0.001）。认知行为疗法在正畸治疗初期的疼痛控制中显示出有效性。该研究的注册号为 ChiCTR-TRC-00000556。
