Department of Food Science and Biotechnology, College of Engineering, Gachon University, Sungnam-Si, Kyunggi-Do, South Korea.
J Virol. 2012 May;86(9):5400-1. doi: 10.1128/JVI.00345-12.
Cronobacter sakazakii infection is particularly harmful to infants, and putative virulence factors of prophage origin have been identified in C. sakazakii. In this study, the phage ENT39118 was isolated from wild-type C. sakazakii; it belongs to the family Siphoviridae. The genomic sequence of phage ENT39118 was composed of circular double-stranded DNA with a length of 39,012 bp. The sequence of ENT39118 showed weak sequence similarity to some reported regions of the prophage sequences in the C. sakazakii BAA-894 genome. To our knowledge, this is the first study of the genomic sequencing and annotation of this temperate phage, which was obtained from a C. sakazakii isolate from powdered infant formula.
阪崎克罗诺杆菌感染对婴儿尤其有害，已在阪崎克罗诺杆菌中鉴定出源自噬菌体的假定毒力因子。在本研究中，从野生型阪崎克罗诺杆菌中分离出噬菌体 ENT39118；它属于肌尾噬菌体科。噬菌体 ENT39118 的基因组序列由长度为 39012bp 的圆形双链 DNA 组成。ENT39118 的序列与阪崎克罗诺杆菌 BAA-894 基因组中某些已报道的噬菌体序列的部分区域显示出较弱的序列相似性。据我们所知，这是首次对从粉状婴儿配方奶粉中分离出的这种温和噬菌体进行基因组测序和注释的研究。
