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蓝舌病病毒血清型 2 分离株的全基因组序列,表明西谱型在印度南部流行。

Complete genome sequence of an isolate of bluetongue virus serotype 2, demonstrating circulation of a Western topotype in southern India.

机构信息

Vector-borne Diseases Programme, Institute for Animal Health, Pirbright, Surrey, United Kingdom.

出版信息

J Virol. 2012 May;86(9):5404-5. doi: 10.1128/JVI.00420-12.

Abstract

Bluetongue virus serotype 2 (IND2003/02) was isolated in Tiruneveli City, Tamil Nadu State, India, and is stored in the Orbivirus Reference Collection at the Institute for Animal Health, Pirbright, United Kingdom. The entire genome of this isolate was sequenced, showing that it is composed of a total of 19,203 bp (all 10 genome segments). This is the first report of the entire genome sequence of a western strain of BTV-2 isolated in India, indicating that this virus has been introduced and is circulating in the region. These data will aid in the development of diagnostics and molecular epidemiology studies of BTV-2 in the subcontinent.

摘要

蓝舌病毒血清型 2(IND2003/02)于印度泰米尔纳德邦蒂鲁内尔维利市分离得到,并保存在英国皮尔布赖特的动物健康研究所的环状病毒参考收藏库中。该分离株的全基因组序列已被测序,表明其由总共 19203 个碱基对(所有 10 个基因组片段)组成。这是在印度分离的西方株 BTV-2 的全基因组序列的首次报道,表明该病毒已传入并在该地区传播。这些数据将有助于在次大陆开发 BTV-2 的诊断和分子流行病学研究。

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