多重 PCR 快速改进肝移植受者血流感染诊断
Multiplex PCR for rapid and improved diagnosis of bloodstream infections in liver transplant recipients.
机构信息
Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
出版信息
J Clin Microbiol. 2012 Jun;50(6):2069-71. doi: 10.1128/JCM.00745-12. Epub 2012 Apr 4.
Abstract
This prospective study evaluated the utility of the SeptiFast (SF) test in detecting 25 clinically important pathogens in 225 blood samples from 170 intensive care unit (ICU) patients with suspected sepsis after liver transplantation (LTX) or after other major abdominal surgery (non-LTX). SF yielded a significantly higher positivity rate in the LTX group (52.3%) than in the non-LTX group (30.5%; P = 0.0009). SF may be a powerful tool for the early diagnosis of bloodstream infections in LTX patients.
摘要
这项前瞻性研究评估了 SeptiFast（SF）检测在检测 170 名疑似肝移植（LTX）或其他主要腹部手术后重症监护病房（ICU）患者 225 份血液样本中 25 种临床重要病原体中的效用。SF 在 LTX 组中的阳性率（52.3%）明显高于非 LTX 组（30.5%；P = 0.0009）。SF 可能是 LTX 患者血流感染早期诊断的有力工具。
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