Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Australia.
J Clin Microbiol. 2012 Jun;50(6):2056-8. doi: 10.1128/JCM.06773-11. Epub 2012 Apr 4.
In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased.
在澳大利亚北部热带地区,约有 20%的金黄色葡萄球菌菌血症是由耐甲氧西林金黄色葡萄球菌(MRSA)引起的。我们前瞻性地评估了对 151 例阳性血培养中聚集性革兰阳性球菌进行 GeneXpert MRSA/SA 检测的结果对临床医生抗生素处方的影响。GeneXpert 结果使 54%的 MRSA 患者更早地获得了合适的万古霉素处方;25%的患者避免了使用万古霉素,16%的患者停止了所有抗生素治疗。