快速检测金黄色葡萄球菌结果对血培养中聚集性革兰阳性球菌患者抗生素处方的影响。
Impact of results of a rapid Staphylococcus aureus diagnostic test on prescribing of antibiotics for patients with clustered gram-positive cocci in blood cultures.
机构信息
Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Australia.
出版信息
J Clin Microbiol. 2012 Jun;50(6):2056-8. doi: 10.1128/JCM.06773-11. Epub 2012 Apr 4.
Abstract
In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased.
摘要
在澳大利亚北部热带地区，约有 20%的金黄色葡萄球菌菌血症是由耐甲氧西林金黄色葡萄球菌（MRSA）引起的。我们前瞻性地评估了对 151 例阳性血培养中聚集性革兰阳性球菌进行 GeneXpert MRSA/SA 检测的结果对临床医生抗生素处方的影响。GeneXpert 结果使 54%的 MRSA 患者更早地获得了合适的万古霉素处方；25%的患者避免了使用万古霉素，16%的患者停止了所有抗生素治疗。
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