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角质形成细胞细胞因子和生长因子。在皮肤免疫和稳态中的作用。

Keratinocyte cytokines and growth factors. Functions in skin immunity and homeostasis.

作者信息

McKenzie R C, Sauder D N

机构信息

Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario, Canada.

出版信息

Dermatol Clin. 1990 Oct;8(4):649-61.

PMID:2249357
Abstract

Evidence has been presented to support the theory that the KC, by virtue of its production of cytokines and growth factors, is an integral component of the immune system. The production of cytokines by the KC is normally carefully regulated in order to maintain normal body homeostasis. Malfunction of the regulatory processes controlling cytokine release may result in the development of skin disease.

摘要

已有证据支持这样一种理论,即角质形成细胞凭借其细胞因子和生长因子的产生,是免疫系统的一个重要组成部分。角质形成细胞产生细胞因子的过程通常受到严格调控,以维持身体的正常内环境稳定。控制细胞因子释放的调节过程出现故障可能会导致皮肤病的发生。

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Dermatol Clin. 1990 Oct;8(4):649-61.
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