Department of Medicine, Division of Infectious Diseases, Henry Ford Hospital, Detroit, MI 48201, USA.
Clin Infect Dis. 2012 May;54(10):1480-4. doi: 10.1093/cid/cis205. Epub 2012 Apr 10.
Oropharyngeal candidiasis (OPC) is among the most common opportunistic infections observed in persons infected with human immunodeficiency virus. A once-daily miconazole 50 mg mucoadhesive buccal tablet (MBT) is a novel delivery system with potent in vitro activity against many Candida species, including some that may be resistant to other azoles. MBT, although more expensive, offers an effective, safe, and well-tolerated topical treatment option for OPC that is administered as a convenient once-daily dose.
口腔念珠菌病（OPC）是人类免疫缺陷病毒感染者中最常见的机会性感染之一。每日一次的咪康唑 50mg 粘膜粘附口腔片剂（MBT）是一种新型的给药系统，对许多念珠菌属具有强大的体外活性，包括一些可能对其他唑类药物耐药的念珠菌属。MBT 虽然更昂贵，但为 OPC 提供了一种有效、安全且耐受性良好的局部治疗选择，每日一次给药，使用方便。
