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口腔念珠菌病的当前治疗方法:文献综述。

Current treatment of oral candidiasis: A literature review.

作者信息

Garcia-Cuesta Carla, Sarrion-Pérez Maria-Gracia, Bagán Jose V

机构信息

Dentist. Postgraduate in Oral Medicine.

Associate profesor of Oral Medicine Unit. Department of Stomatology. University of Valencia.

出版信息

J Clin Exp Dent. 2014 Dec 1;6(5):e576-82. doi: 10.4317/jced.51798. eCollection 2014 Dec.

Abstract

Candidiasis or oral candidosis is one of the most common human opportunistic fungal infections of the oral cavity. This pathology has a wide variety of treatment which has been studied until these days. The present study offers a literature review on the treatment of oral candidiasis, with the purpose of establish which treatment is the most suitable in each case. Searching the 24 latest articles about treatment of candidiasis it concluded that the incidence depends on the type of the candidiasis and the virulence of the infection. Although nystatin and amphotericin b were the most drugs used locally, fluconazole oral suspension is proving to be a very effective drug in the treatment of oral candidiasis. Fluconazole was found to be the drug of choice as a systemic treatment of oral candidiasis. Due to its good antifungal properties, its high acceptance of the patient and its efficacy compared with other antifungal drugs. But this drug is not always effective, so we need to evaluate and distinguish others like itraconazole or ketoconazole, in that cases when Candida strains resist to fluconazole. Key words:Candidiasis, treatment, miconazole, fluconazole, nystatin.

摘要

念珠菌病或口腔念珠菌病是人类口腔最常见的机会性真菌感染之一。这种病症有多种治疗方法,至今仍在研究。本研究对口腔念珠菌病的治疗进行了文献综述,目的是确定每种情况下最适合的治疗方法。通过检索24篇关于念珠菌病治疗的最新文章得出结论,发病率取决于念珠菌病的类型和感染的毒力。尽管制霉菌素和两性霉素B是最常用的局部用药,但氟康唑口服混悬液在治疗口腔念珠菌病方面被证明是一种非常有效的药物。氟康唑被发现是口腔念珠菌病全身治疗的首选药物。由于其良好的抗真菌特性、患者的高接受度以及与其他抗真菌药物相比的疗效。但这种药物并不总是有效,所以在念珠菌菌株对氟康唑耐药的情况下,我们需要评估和区分其他药物,如伊曲康唑或酮康唑。关键词:念珠菌病、治疗、咪康唑、氟康唑、制霉菌素

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Current treatment of oral candidiasis: A literature review.口腔念珠菌病的当前治疗方法:文献综述。
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