Center for Family and Community Medicine, Karolinska Institutet, Huddinge, Sweden.
J Health Psychol. 2013 Mar;18(3):311-20. doi: 10.1177/1359105311435428. Epub 2012 Apr 10.
Poor subjective health has been associated with higher levels of inflammatory cytokines. We investigated whether such an association would apply to women of the general population. Levels of cytokines, affect and subjective health were assessed in 347 women of the general population aged 45 to 90 years. Higher levels of interleukin-6 were associated with poor subjective health, especially in participants over 65 years of age. Positive affect was a more robust determinant of subjective health than negative affect. The presence of low-grade inflammation and absence of positive affect, rather than presence of negative affect, may be important determinants of subjective health.
较差的主观健康状况与更高水平的炎性细胞因子有关。我们研究了这种关联是否适用于一般人群中的女性。我们评估了 347 名年龄在 45 至 90 岁之间的一般人群女性的细胞因子水平、情绪和主观健康状况。白细胞介素-6 水平较高与主观健康状况较差相关，尤其是在 65 岁以上的参与者中。积极情绪比消极情绪更能显著影响主观健康。低度炎症的存在和积极情绪的缺失，而不是消极情绪的存在，可能是主观健康的重要决定因素。
