Iester Michele, De Feo Fabio, Douglas Gordon R
Department of Ophthalmology, University of British Columbia, Vancouver, BC, Canada V5Z 3N9.
J Ophthalmol. 2012;2012:327326. doi: 10.1155/2012/327326. Epub 2012 Feb 8.
Purpose. To determine whether the patterns of visual field damage between high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) are equivalent. Methods. In this retrospective cross-sectional study, fifty-one NTG and 57 HTG patients were recruited. For each recruited patient only the left eye was chosen. Glaucomatous patients had abnormal visual fields and/or glaucomatous changes at the optic nerve head. They were classified as HTG or NTG on the basis of intraocular pressure (IOP) measurements. Patients' visual fields were analyzed by using Humphrey Field Analyzer (HFA), program 30-2, full threshold. The visual field sensitivity values and the pattern deviation map values of the 72 tested points were considered. Then a pointwise analysis and an area analysis, based on the Glaucoma Hemifield test criteria, were performed, and a comparison between the two subgroups was made by Student's t test. Results. Between NTG and HTG, no significant difference was found pointwise for almost all the visual field points, except for two locations. One was under the blind spot, and the other was in the inferior hemifield around the twenty-degree position. When area analysis was considered, three areas showed a significantly different sensitivity between HTG and NTG. Conclusions. These data suggested that there was no relevant difference in the pointwise analysis between NTG and HTG; however, when visual field areas were compared, no difference in paracentral areas was found between NTG and HTG, but superior nasal step and inferior and superior scotomata showed to be deeper in HTG than in NTG.
目的。确定高眼压性青光眼（HTG）和正常眼压性青光眼（NTG）之间视野损害模式是否等同。方法。在这项回顾性横断面研究中，招募了51例NTG患者和57例HTG患者。对于每位招募的患者，仅选择左眼。青光眼患者视野异常和/或视神经乳头有青光眼性改变。根据眼压（IOP）测量结果将他们分为HTG或NTG。使用Humphrey视野分析仪（HFA）程序30 - 2全阈值分析患者的视野。考虑72个测试点的视野敏感度值和模式偏差图值。然后基于青光眼半视野测试标准进行逐点分析和区域分析，并通过学生t检验对两个亚组进行比较。结果。在NTG和HTG之间，几乎所有视野点逐点分析均未发现显著差异，但有两个位置除外。一个在盲点下方，另一个在20度位置周围的下半视野。当进行区域分析时，三个区域显示HTG和NTG之间敏感度有显著差异。结论。这些数据表明，NTG和HTG在逐点分析中没有相关差异；然而，当比较视野区域时，NTG和HTG在旁中心区域未发现差异，但HTG的鼻上阶梯以及下和上暗点比NTG更深。
