Secchi A G, Tognon M S, Maselli C
Institute of Ophthalmology, University of Padova, School of Medicine.
Int Ophthalmol. 1990 Oct;14(5-6):395-9. doi: 10.1007/BF00163565.
Seven patients affected by bilateral inflammatory serpiginous choroiditis have been treated with Cyclosporine-A for 6-21 months. Nine out of the fourteen eyes showed a significant improvement in their visual acuity; five eyes did not change. Cyclosporine-A may, therefore, be considered effective in the treatment of this disease. Its usefulness seems to be greater when the serpiginous choroiditis is in its 'acute' stage; 'chronic' stages, however, also seem to improve under treatment. Its main indication is, in our opinion, the involvement of the macular region of the 'second' eye, when the 'first' eye is already damaged. We consider Cyclosporine-A, in these situations, to be a first choice treatment.
七名双侧炎症性匐行性脉络膜炎患者接受了环孢素A治疗，疗程为6至21个月。十四只眼中有九只眼的视力有显著改善；五只眼视力未变。因此，环孢素A可被认为对治疗这种疾病有效。当匐行性脉络膜炎处于“急性”期时，其效用似乎更大；然而，“慢性”期在治疗下似乎也有所改善。我们认为，其主要适应证是当“第一只”眼已受损时，“第二只”眼的黄斑区受累。在这些情况下，我们认为环孢素A是首选治疗方法。
