Division of Gastroenterology, University of South Alabama College of Medicine, Mobile, AL 36693, USA.
Gastroenterol Clin North Am. 2012 Jun;41(2):315-23. doi: 10.1016/j.gtc.2012.01.005. Epub 2012 Feb 14.
Capsule endoscopy is a relatively new technology available in the investigation of IBD. Its place in the algorithm of evaluating IBD is being refined. Capsule endoscopy has the ability to visualize the entire SB with very few complications. It is a sensitive test for the diagnosis of mucosal changes, but should be viewed as complementary to other radiologic evaluations, such as CTE and MRE. Capsule endoscopy is nonspecific and its findings have to be interpreted with caution and in the right clinical setting, because up to one fifth of normal individuals may have subtle changes in the small intestine. Care should also be taken to exclude NSAID use because it mimics findings seen in CD. Capsule endoscopy is an exciting technology that opened the possibility of the evaluation of the SB in the era of “deep remission.” It is best applied in patients with a high clinical suspicion for IBD after unremarkable colonoscopy with terminal ileal intubation and radiologic investigation.
胶囊内镜是一种用于 IBD 检查的新兴技术。它在 IBD 评估算法中的地位正在不断完善。胶囊内镜具有可视化整个 SB 的能力,且并发症极少。它是一种用于诊断黏膜变化的敏感检测手段,但应被视为对其他影像学评估(如 CTE 和 MRE)的补充。胶囊内镜是非特异性的,其发现必须在正确的临床环境下谨慎解读,因为多达五分之一的正常个体可能在小肠中存在细微变化。此外,还应注意排除 NSAID 的使用,因为它会模仿 CD 中观察到的发现。胶囊内镜是一项令人兴奋的技术,它为“深度缓解”时代 SB 的评估开辟了可能。它最好应用于在无明显异常的结肠镜检查联合末端回肠插管和影像学检查后,临床高度怀疑 IBD 的患者。