Jefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Clin Geriatr Med. 2012 May;28(2):173-86. doi: 10.1016/j.cger.2012.01.002.
The elderly are at risk for polypharmacy, which is associated with significant consequences such as adverse effects, medication nonadherence, drug-drug and drug-disease interactions, and increased risk of geriatric syndromes. Providers should evaluate all existing medications at each patient visit for appropriateness and weigh the risks and benefits of starting new medications to minimize polypharmacy.
老年人面临着多种药物治疗的风险,这与许多不良后果相关,如不良反应、药物不依从、药物-药物和药物-疾病相互作用,以及老年综合征风险增加。医务人员应在每次就诊时评估所有现有药物的适宜性,并权衡开始新药物治疗的风险和获益,以尽量减少多种药物治疗。