Bongard V, Dallongeville J, Arveiler D, Ruidavets J-B, Cottel D, Wagner A, Ferrières J
Inserm UMR1027, département d'épidémiologie, économie de la santé et santé publique, faculté de médecine, 31073 Toulouse cedex, France.
Ann Cardiol Angeiol (Paris). 2012 Aug;61(4):239-44. doi: 10.1016/j.ancard.2012.03.003. Epub 2012 Mar 23.
Chronic kidney disease (CKD) is a major public health issue. In France, few studies have evaluated CKD prevalence. The objective of the MONA LISA study was to estimate and to characterize CKD in three representative cross-sectional surveys in subjects aged 35-74.9 years. CKD was defined as subjects having MDRD glomerular filtration rate lower than 60 mL/min/1.73 m(2). Prevalence of CKD in MONA LISA was standardized according to the French population. A multiple logistic regression analysis was performed in order to find independent factors associated to CKD. The French estimate of CKD prevalence was 8.2% (95% confidence interval: 7.4-8.9%), that is 2,454,548 (95% confidence interval: 2,215,080-2,664,082) subjects aged 35-74.9 years. Factors significantly and independently associated to CKD were older age, hypertension and dyslipidemias. In conclusion, the MONA LISA study evaluated for the first time in France CKD prevalence in subjects aged 35-74.9 years. This prevalence probably underestimates the real CKD size due to selection bias present in every representative cross-sectional survey.
