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类癌肿瘤

Carcinoid tumors.

作者信息

Nwiloh J O, Pillarisetty S, Moscovic E A, Freeman H P

机构信息

Department of Surgery, Harlem Hospital Center, College of Physicians and Surgeons, Columbia University, New York, NY 10037.

出版信息

J Surg Oncol. 1990 Dec;45(4):261-4. doi: 10.1002/jso.2930450410.

DOI:10.1002/jso.2930450410
PMID:2250476
Abstract

The authors carried out a retrospective study of 32 patients (23 M, 9 F) with carcinoid tumors who were diagnosed and treated at Harlem Hospital Center, New York, from 1967 to 1988. All the patients were black and the commonest sites were the ileum (28.1%), rectosigmoid and rectum (21.9%), and the appendix and lung (15.6% each). Metastasis correlated with site, size, and depth of the primary tumor and occurred in 12 patients (38%), most frequently to the regional lymph nodes and liver. Carcinoid syndrome developed in 12.5% (3 F, 1 M). Surgical resection for cure or palliation was the mainstay of treatment. Overall 5 year survival rate was 66%, and for those with metastases was 0%. The poorer survival rates are probably related to the socioeconomic status of our patient population. The only observed racial difference compared to other series is the preponderance of males, and the disproportionately higher ratio of females with the carcinoid syndrome.

摘要

作者对1967年至1988年期间在纽约哈莱姆医院中心诊断和治疗的32例类癌患者(23例男性,9例女性)进行了一项回顾性研究。所有患者均为黑人,最常见的发病部位是回肠(28.1%)、直肠乙状结肠和直肠(21.9%)以及阑尾和肺(各占15.6%)。转移与原发肿瘤的部位、大小和深度相关,12例患者(38%)发生了转移,最常见的转移部位是区域淋巴结和肝脏。类癌综合征在12.5%的患者(3例女性,1例男性)中出现。手术切除以治愈或缓解病情是主要的治疗方法。总体5年生存率为66%,有转移的患者5年生存率为0%。生存率较低可能与我们患者群体的社会经济状况有关。与其他系列相比,唯一观察到的种族差异是男性占多数,以及患类癌综合征的女性比例过高。

相似文献

1
Carcinoid tumors.类癌肿瘤
J Surg Oncol. 1990 Dec;45(4):261-4. doi: 10.1002/jso.2930450410.
2
[Carcinoid tumors, carcinoid syndromes and related tumors (104 cases)].[类癌肿瘤、类癌综合征及相关肿瘤(104例)]
Helv Chir Acta. 1980 Dec;47(5):601-5.
3
The carcinoid tumour.
Aust N Z J Surg. 1979 Jun;49(3):317-26. doi: 10.1111/j.1445-2197.1979.tb07672.x.
4
Gastrointestinal carcinoids and the malignant carcinoid syndrome.胃肠道类癌与恶性类癌综合征
Surg Gynecol Obstet. 1981 Mar;152(3):268-72.
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Carcinoids and carcinoid syndrome.
Am J Med. 1987 May 29;82(5B):4-16. doi: 10.1016/0002-9343(87)90422-0.
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Prognosis and survival in patients with gastrointestinal tract carcinoid tumors.胃肠道类癌肿瘤患者的预后与生存情况
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[Carcinoid tumors].[类癌肿瘤]
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Gastrointestinal carcinoid tumors: diagnosis and treatment.胃肠道类癌肿瘤:诊断与治疗
Chirurgia (Bucur). 2010 Nov-Dec;105(6):759-66.
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Current management of gastrointestinal carcinoid tumors.胃肠道类癌肿瘤的当前管理
J Gastrointest Surg. 2004 Sep-Oct;8(6):742-56. doi: 10.1016/j.gassur.2004.04.010.
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Gastrointestinal carcinoid tumors.胃肠道类癌肿瘤。
Rev Esp Enferm Dig. 2010 Sep;102(9):533-7. doi: 10.4321/s1130-01082010000900004.

引用本文的文献

1
Malignant neoplasms of the appendix.阑尾恶性肿瘤
Int J Colorectal Dis. 2007 Oct;22(10):1239-48. doi: 10.1007/s00384-007-0304-0. Epub 2007 Apr 20.
2
Carcinoid tumors of the appendix.阑尾类癌肿瘤
Ann Surg. 1993 Apr;217(4):385-90. doi: 10.1097/00000658-199304000-00010.