Besson A, Nguyen T H, Saegesser F
Helv Chir Acta. 1980 Dec;47(5):601-5.
One hundred and four consecutive cases of carcinoid among 194 APUD-omas (cerebral and gynecological tumours expected) are presented. Localization is as follows: bronchopulmonary (21%), duodenum (5,5%), small intestine (19%), Meckel's diverticulum (5,5%), appendix (39%), colorectal (5,5%), other (4,5%). Average age at diagnosis is very different for each localization of carcinoid tumour, as is prognosis: in our material, 33% of cases had an infiltrative tumour, 17% had lymph nodes metastases and 16% hepatic metastases. All 15 patients with carcinoidosis died but their survival varied considerably in length (from a few weeks to 21 years after the beginning of carcinoidosis). In addition, 3 patients presented with the Zollinger-Ellison syndrome, 2 of them having an atypical or probable form of the MEN I syndrome.
本文报告了194例APUD瘤(预计包括脑和妇科肿瘤)中连续的104例类癌病例。其定位如下:支气管肺(21%)、十二指肠(5.5%)、小肠(19%)、梅克尔憩室(5.5%)、阑尾(39%)、结直肠(5.5%)、其他(4.5%)。类癌肿瘤的每个定位在诊断时的平均年龄以及预后都有很大差异:在我们的资料中,33%的病例有浸润性肿瘤,17%有淋巴结转移,16%有肝转移。所有15例类癌综合征患者均死亡,但他们的生存时间差异很大(从类癌综合征开始后的几周至21年)。此外,3例患者出现佐林格-埃利森综合征,其中2例患有非典型或可能的MEN I综合征。