Besson A, Nguyen T H, Saegesser F
Helv Chir Acta. 1980 Dec;47(5):601-5.
One hundred and four consecutive cases of carcinoid among 194 APUD-omas (cerebral and gynecological tumours expected) are presented. Localization is as follows: bronchopulmonary (21%), duodenum (5,5%), small intestine (19%), Meckel's diverticulum (5,5%), appendix (39%), colorectal (5,5%), other (4,5%). Average age at diagnosis is very different for each localization of carcinoid tumour, as is prognosis: in our material, 33% of cases had an infiltrative tumour, 17% had lymph nodes metastases and 16% hepatic metastases. All 15 patients with carcinoidosis died but their survival varied considerably in length (from a few weeks to 21 years after the beginning of carcinoidosis). In addition, 3 patients presented with the Zollinger-Ellison syndrome, 2 of them having an atypical or probable form of the MEN I syndrome.
本文报告了194例APUD瘤（预计包括脑和妇科肿瘤）中连续的104例类癌病例。其定位如下：支气管肺（21%）、十二指肠（5.5%）、小肠（19%）、梅克尔憩室（5.5%）、阑尾（39%）、结直肠（5.5%）、其他（4.5%）。类癌肿瘤的每个定位在诊断时的平均年龄以及预后都有很大差异：在我们的资料中，33%的病例有浸润性肿瘤，17%有淋巴结转移，16%有肝转移。所有15例类癌综合征患者均死亡，但他们的生存时间差异很大（从类癌综合征开始后的几周至21年）。此外，3例患者出现佐林格-埃利森综合征，其中2例患有非典型或可能的MEN I综合征。
