Rout Laxmidhar, Regati Sridhar, Zhao Cong-Gui
Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Adv Synth Catal. 2011 Dec 1;353(18):3340-3346. doi: 10.1002/adsc.201100605. Epub 2011 Dec 6.
Efficient methods for the direct arylation and deacylative arylation of β-ketophosphonates with iodoarenes in presence of a copper(I) or a copper(II) salt as the catalysts were developed. The corresponding α-arylphosphonates were obtained in high yields. A tentative mechanism for the deacylative arylation reaction was proposed on the basis of the experimental data.
开发了在铜(I)或铜(II)盐作为催化剂存在下,β-酮膦酸酯与碘代芳烃直接芳基化和脱酰基芳基化的有效方法。以高收率得到了相应的α-芳基膦酸酯。根据实验数据提出了脱酰基芳基化反应的初步机理。