Huang Cheng, Tang Xu, Fu Hua, Jiang Yuyang, Zhao Yufen
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, PR China.
J Org Chem. 2006 Jun 23;71(13):5020-2. doi: 10.1021/jo060492j.
We have developed a convenient and efficient approach for P-arylation of organophosphorus compounds containing P-H. Using commercially available and inexpensive proline and pipecolinic acid as the ligands greatly improved the efficiency of the coupling reactions, so the method can provide an entry to arylphosphonates, arylphosphinates and arylphosphine oxides.
我们已经开发出一种简便高效的方法用于含P-H的有机磷化合物的P-芳基化反应。使用市售且廉价的脯氨酸和哌啶酸作为配体极大地提高了偶联反应的效率，因此该方法可用于制备芳基膦酸酯、芳基亚膦酸酯和芳基氧化膦。
