Duggan Derek, Zhong Sheng, Rivera Eric, Arnold Roland, Simmons Eric
Department of Endodontics, UNC School of Dentistry, Chapel Hill, NC 27599, USA.
Int J Dent. 2012;2012:365231. doi: 10.1155/2012/365231. Epub 2012 Feb 22.
Objective. This study compared the leakage resistance of a New Sealer Prototype (NSP) with a traditional sealer (AH 26) in Resilon-filled roots subjected to a bacterial challenge. Study Design. 41 roots were instrumented to ISO size 50 apically. Group 1 (n = 20) contained Resilon and AH 26 sealer and roots in group 2 (n = 21) contained Resilon and NSP. Roots were embedded in a dual-chamber model with the upper chamber containing Streptococcus mutans inoculum. Evidence of bacterial penetration was observed for 1 month. Fisher's Test was used to analyze the data. Results. 8 of 20 roots (40%) in the AH 26 group demonstrated leakage whereas 3 of 21 roots (14%) in the NSP group leaked. The difference in leakage rates was not statistically significant (P = 0.053). Conclusion. The traditional sealer (AH 26) demonstrated increased leakage rates compared to the New Sealer Prototype (NSP), but the difference did not reach statistical significance in this study.
目的。本研究比较了新型封闭剂原型（NSP）与传统封闭剂（AH 26）在受细菌挑战的Resilon充填根管中的抗渗漏性。研究设计。41颗根管根尖预备至ISO 50号。第1组（n = 20）包含Resilon和AH 26封闭剂，第2组（n = 21）的根管包含Resilon和NSP。根管嵌入双腔模型，上腔含有变形链球菌接种物。观察细菌渗透证据1个月。采用Fisher检验分析数据。结果。AH 26组20颗根管中有8颗（40%）出现渗漏，而NSP组21颗根管中有3颗（14%）渗漏。渗漏率差异无统计学意义（P = 0.053）。结论。与新型封闭剂原型（NSP）相比，传统封闭剂（AH 26）的渗漏率有所增加，但在本研究中差异未达到统计学意义。
