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为何糖皮质激素类固醇仍应保留在禁用物质清单中:运动医学视角。

Why glucocorticosteroids should remain in the list of prohibited substances: a sports medicine viewpoint.

出版信息

Int J Immunopathol Pharmacol. 2012 Jan-Mar;25(1):19-24. doi: 10.1177/039463201202500103.

DOI:10.1177/039463201202500103
PMID:22507313
Abstract

In addition to their therapeutic applications, glucocorticosteroids have been widely used and abused in the belief that these substances may enhance athletic performance. Analysis of athlete urine samples by antidoping laboratories around the world support this conclusion. It is commonly accepted in medical practice to use local glucocorticosteroid injections in the treatment of non-infectious local musculotendinous inflammatory conditions conveying symptom relief and often a speedier return to sporting activity. This practice is not to be considered illicit, but sports physicians must accept that such an intervention is not in itself an immediate cure and that an athlete will still require a period of recuperation before continuing sporting activity. How long such a period of recuperation should last is a matter of conjecture and there is little concrete data to support what is, or what is not, an acceptable period of inactivity. In the interest of athlete safety, we would propose to maintain systemic glucocorticosteroids on the World Anti-Doping Agency's (WADA) list of prohibited substances, both in and out-of-competition as well as a mandatory period of 48 hours of rest from play after receiving a local glucocorticosteroid injection.

摘要

除了治疗应用外,人们还广泛地将糖皮质激素用于增强运动表现的信念,而这些物质可能会增强运动表现。世界各地的反兴奋剂实验室对运动员尿液样本的分析支持了这一结论。在医学实践中,人们普遍接受使用局部糖皮质激素注射治疗非传染性局部肌肉腱炎症况,以缓解症状并通常更快地恢复运动活动。这种做法不应被视为非法,但运动医学医生必须接受这样的干预本身并不是立即治愈,运动员在继续运动活动之前仍需要一段时间的恢复。这种恢复期应该持续多久是一个猜测的问题,几乎没有具体的数据来支持什么是,或者什么不是,可接受的不活动期。为了运动员的安全,我们建议将全身糖皮质激素保留在世界反兴奋剂机构(WADA)的禁用物质清单中,无论是在比赛中还是比赛外,并且在接受局部糖皮质激素注射后必须休息 48 小时才能继续比赛。

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