Department of Dermatology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA.
Dermatology. 2012;224(2):110-4. doi: 10.1159/000337210. Epub 2012 Apr 12.
Axillary web syndrome (AWS) is defined as a cord-like structure extending from the axilla to the medial arm following axillary surgery in women with breast cancer. There is only limited literature on the pathogenesis of this syndrome and the etiology of the cord. A 57-year-old man presented with a band-like skin depression and tightness over the medial aspect of his arm extending from the axilla to the antecubital fossa following development of a furuncle in the ipsilateral axilla. Histopathologic examination of the 'band' revealed fibroblastic proliferation surrounding the lymphatic vessel which was identified by presence of an obvious valve as well as positive staining for D2-40, a specific marker for lymphatic endothelium. This is the first report of AWS following axillary furunculosis. This case adds to the limited data on the histopathology of AWS, further confirming the etiology of the 'cord' to be of lymphatic origin.
腋网综合征（AWS）定义为乳腺癌女性腋窝手术后从腋窝延伸至内侧臂的索状结构。关于该综合征和索带的发病机制，文献资料有限。一名 57 岁男性，在同侧腋窝疖发展后，出现从腋窝延伸至肘前窝的臂内侧带状皮肤凹陷和紧绷。对“带”的组织病理学检查显示，成纤维细胞围绕淋巴管增殖，淋巴管通过明显的瓣膜以及 D2-40（淋巴管内皮的特异性标志物）的阳性染色来识别。这是 AWS 继腋窝痈疽后的首例报道。该病例增加了 AWS 组织病理学的有限数据，进一步证实了“索带”的病因是淋巴起源。
