Brain Tumor Center at the University of Cincinnati Neuroscience Institute, Cincinnati, Ohio, USA.
Laryngoscope. 2012 Jul;122(7):1526-31. doi: 10.1002/lary.23347. Epub 2012 Apr 16.
OBJECTIVES/HYPOTHESIS: Evaluate sexual dysfunction in patients after treatment for head and neck cancer.
Single-institution cross-sectional study.
Our modified Sexual Adjustment Questionnaire was administered to 42 patients (mean age, 55.1 years) and included seven questions (total score, 7-35). Based on sexual satisfaction ratings, we categorized three groups as unsatisfied (7-16), satisfied (17-25), and very satisfied (26-35). Clinical information was obtained by reviewing medical records. Bivariate analysis tested associations between sexual satisfaction and patient-related factors (e.g., sex, age, site/cancer stage, treatment, time between treatment and survey, partner, alcohol/tobacco consumption). Pearson correlation was used to analyze two continuous variables, and multivariate logistic regression analysis was used to evaluate the independent impact of each factor.
All 42 patients rated that head and neck cancer negatively impacted their sexual relationships, including 21 (50%) rating effects as negative or extremely negative. Men reported higher satisfaction scores with sexual function (mean ± standard deviation) than women (19.9 ± 5.0 vs. 16.3 ± 6.5, respectively; P = .06). Respondents with partners reported higher scores than those without partners (19.9 ± 5.3 vs. 14.1 ± 4.4, respectively; P = .01). When the survey was administered (median, 12 months; range, 4-33 months) after the first treatment, mean score was 19; 57% of respondents were sexually satisfied, 31% were unsatisfied, and 12% were very satisfied. Instrument reliability was .82 (Cronbach alpha).
Patients who are male and ≤ 60 years have a higher probability of sexual satisfaction during recovery. Our sexual dysfunction questionnaire will be administered in further prospective studies in patients with head and neck cancer.
目的/假设：评估头颈部癌症治疗后患者的性功能障碍。
单机构横断面研究。
我们使用改良后的性调整问卷对 42 名患者（平均年龄 55.1 岁）进行了调查，问卷包含七个问题（总分为 7-35 分）。根据性满意度评分，我们将患者分为三组：不满意（7-16 分）、满意（17-25 分）和非常满意（26-35 分）。通过查阅病历获取临床信息。采用双变量分析测试性满意度与患者相关因素（如性别、年龄、部位/癌症分期、治疗、治疗与调查之间的时间、伴侣、酒精/烟草消费）之间的关联。采用 Pearson 相关分析连续变量之间的关系，采用多元逻辑回归分析评估每个因素的独立影响。
所有 42 名患者均表示头颈部癌症对其性关系产生负面影响，其中 21 名（50%）患者认为影响为负面或非常负面。男性报告的性功能满意度评分（平均值±标准差）高于女性（分别为 19.9±5.0 与 16.3±6.5；P=0.06）。有伴侣的受访者报告的评分高于无伴侣的受访者（分别为 19.9±5.3 与 14.1±4.4；P=0.01）。首次治疗后（中位数为 12 个月，范围为 4-33 个月）进行调查时，平均评分为 19 分；57%的受访者对性生活感到满意，31%的受访者不满意，12%的受访者非常满意。该工具的可靠性为 0.82（Cronbach α）。
≤60 岁的男性患者在康复期间更有可能获得性满足。我们的性功能障碍问卷将在头颈部癌症患者的进一步前瞻性研究中使用。
