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头颈癌幸存者的生活质量:一项横断面调查。

Quality of life in head and neck cancer survivors: a cross-sectional survey.

作者信息

Chaukar Devendra A, Walvekar Rohan R, Das Ashok K, Deshpande Mandar S, Pai Prathamesh S, Chaturvedi Pankaj, Kakade Anagha, D'Cruz Anil K

机构信息

Department of Head and Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, India.

出版信息

Am J Otolaryngol. 2009 May-Jun;30(3):176-80. doi: 10.1016/j.amjoto.2008.05.001. Epub 2008 Oct 1.

DOI:10.1016/j.amjoto.2008.05.001
PMID:19410123
Abstract

PURPOSE

Head and neck cancer (HNC) survivors have substantial psychological distress in addition to treatment-related side effects. This study examines the long-term quality of life (QOL) of HNC survivors in a busy tertiary care center.

MATERIAL AND METHODS

A prospective, cross-sectional survey was conducted studying 212 HNC survivors 1 year after completion of their treatment at a tertiary cancer center. Quality of life assessments were performed using the 2 standardized health-related QOL questionnaires: The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 and The Quality of Life Questionnaire Head and Neck Cancer Module.

RESULTS

The overall global QOL rating for the study cohort was satisfactory. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 scores showed that the domains where most patients faired poorly included financial difficulties (54%), appetite loss (36%), fatigue (33%), and cough (30%). The Quality of Life Questionnaire Head and Neck Cancer Module scale identified the domains with poor scores to be dry mouth (64%), dental problems (42%), sticky saliva (40%), cough (39%), and problems with mouth opening (32%). Patients with early-stage tumors and those treated with surgery alone had significantly better QOL scores when compared with advanced stage tumors and patients receiving either radiation alone or multimodality treatment, respectively.

CONCLUSIONS

Quality of life questionnaires provide a medium for patients to effectively communicate with their physician in a busy tertiary care facility and provide an insight into the physical, psychological, and social problems affecting our patients which can then direct future interventions.

摘要

目的

头颈癌(HNC)幸存者除了有与治疗相关的副作用外,还存在严重的心理困扰。本研究调查了一家繁忙的三级医疗中心中HNC幸存者的长期生活质量(QOL)。

材料与方法

在一家三级癌症中心,对212名完成治疗1年后的HNC幸存者进行了一项前瞻性横断面调查。使用2份标准化的与健康相关的生活质量问卷进行生活质量评估:欧洲癌症研究与治疗组织生活质量问卷核心30项以及头颈癌生活质量问卷模块。

结果

该研究队列的总体全球生活质量评分令人满意。欧洲癌症研究与治疗组织生活质量问卷核心30项得分显示,大多数患者表现较差的领域包括经济困难(54%)、食欲减退(36%)、疲劳(3%)和咳嗽(30%)。头颈癌生活质量问卷模块量表确定得分较低的领域为口干(64%)、牙齿问题(42%)、唾液黏稠(40%)、咳嗽(39%)和张口困难(32%)。与晚期肿瘤患者以及分别接受单纯放疗或多模式治疗的患者相比,早期肿瘤患者和仅接受手术治疗的患者的生活质量得分显著更高。

结论

生活质量问卷为患者在繁忙的三级医疗设施中与医生有效沟通提供了一种媒介,并深入了解了影响我们患者的身体、心理和社会问题,从而为未来的干预措施提供指导。

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