Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Minas Gerais, Brazil.
J Periodontol. 2013 Mar;84(3):287-94. doi: 10.1902/jop.2012.120165. Epub 2012 Apr 23.
Dentin hypersensitivity (DH) is a painful, exaggerated response to normal stimuli, such as cold, sweetness, and brushing. The aim of the present controlled, randomized, double-masked, non-inferiority clinical trial is to evaluate the effectiveness of cyanoacrylate in the treatment of DH when compared to the application of low-intensity laser.
The study includes 434 sensitive teeth from 62 patients. A total of 216 teeth were treated with laser and 218 with cyanoacrylate. A numeric rating scale was used to record the parameters of pain related to the stimuli at baseline and after the treatment at intervals of 24 hours and 30, 90, and 180 days.
Both groups had significant reductions in DH. However, there was no significant difference between the two groups ≤6 months. Intragroup analysis showed that the effect of cyanoacrylate obtained at 24 hours remained for 90 days in response to air-jet test and 30 days for cold-spray test. There was a statistically significant difference between all other intragroup comparisons at the time intervals (P <0.001).
It was concluded that cyanoacrylate is as effective as low-intensity laser in reducing DH. In addition, it is a more accessible and low-cost procedure and can be safely used in the treatment of DH.
牙本质过敏症（DH）是一种对正常刺激（如冷、甜、刷牙）产生疼痛、过度反应的病症。本对照、随机、双盲、非劣效性临床试验旨在评估氰基丙烯酸酯治疗牙本质过敏症的有效性，与低强度激光应用相比。
该研究共纳入 62 名患者的 434 颗敏感牙齿。共有 216 颗牙齿接受激光治疗，218 颗牙齿接受氰基丙烯酸酯治疗。使用数字评分量表记录基线时和治疗后 24 小时、30 天、90 天和 180 天与刺激相关的疼痛参数。
两组患者的 DH 均有明显减轻。然而，两组患者在 ≤6 个月时无显著差异。组内分析显示，在空气喷溅试验中，氰基丙烯酸酯在 24 小时获得的效果可维持 90 天，而在冷喷试验中则可维持 30 天。在所有其他组内比较的时间间隔内均存在统计学显著差异（P <0.001）。
氰基丙烯酸酯在减轻 DH 方面与低强度激光同样有效。此外，它是一种更容易获得且成本更低的治疗方法，可安全用于治疗 DH。
