Ko Y, Park J, Kim C, Park J, Baek S H, Kook Y A
Department of Periodontics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
J Oral Rehabil. 2014 Jul;41(7):523-31. doi: 10.1111/joor.12170. Epub 2014 Apr 10.
Dentin hypersensitivity (DH) is defined as pain derived from exposed dentin in response to chemical, thermal, tactile, or osmotic stimuli that cannot be explained as having arisen from any other dental defect or disease. The aim of this trial was to test the efficacy and the safety of a low-level laser-emitting toothbrush on management of DH. A prospective, double blind, randomised clinical trial was designed; 96 individuals with hypersensitive teeth without caries or fracture were selected as subjects. The subjects were randomly allocated to either the test group with the 635 nm per 6 mW laser-emitting toothbrush, or the control group with the 635 nm per 12.9 μW light-emitting diode (LED) toothbrush. An air blast was applied with a dental air syringe held 3 mm away from the selected tooth and a visual analogue scale (VAS: 0-10) was used to quantify subjective pain. Assessments were completed at a screening visit and after 2-week and 4-week of using a test/control toothbrush. Results demonstrated that the use of both control and test toothbrushes resulted in decreased discomfort after 4 weeks. In the test group, pain intensity scores decreased from 5.8 ± 1.2 to 2.3 ± 1.6, and in the control group, the scores decreased from 6.4 ± 1.3 to 5.5 ± 2.0 (P < 0.05). This decrease was significantly greater in the test group. There were no significant adverse events or side effects. It was concluded that the use of the low-level laser emitting toothbrush is a safe and effective treatment option for the management of DH.
牙本质过敏症（DH）被定义为因暴露的牙本质对化学、热、触觉或渗透刺激产生的疼痛，且这种疼痛无法用任何其他牙齿缺陷或疾病来解释。本试验的目的是测试一种低水平激光牙刷治疗牙本质过敏症的疗效和安全性。设计了一项前瞻性、双盲、随机临床试验；选择96名无龋齿或骨折的牙齿过敏个体作为受试者。受试者被随机分配到使用每6毫瓦635纳米激光牙刷的试验组或使用每12.9微瓦635纳米发光二极管（LED）牙刷的对照组。用牙科气枪在距离选定牙齿3毫米处吹气，并使用视觉模拟评分法（VAS：0 - 10）量化主观疼痛。在筛选访视时以及使用试验/对照牙刷2周和4周后完成评估。结果表明，使用对照组和试验组牙刷4周后不适感均有所减轻。试验组疼痛强度评分从5.8±1.2降至2.3±1.6，对照组评分从6.4±1.3降至5.5±2.0（P<0.05）。试验组的这种下降更为显著。未出现明显不良事件或副作用。得出的结论是，使用低水平激光牙刷是治疗牙本质过敏症的一种安全有效的选择。
