Stony Brook University, 314 Old Engineering, Stony Brook, NY 11794-2275, USA.
J Mater Sci Mater Med. 2012 Oct;23(10):2359-68. doi: 10.1007/s10856-012-4633-3. Epub 2012 Apr 18.
In this study, strontium-doped calcium phosphate coatings were deposited by electrochemical deposition and plasma spray under different process parameters to achieve various coating morphologies. The coating composition was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy while the cytocompatibility and bioactivity of the strontium-doped calcium phosphate coatings were evaluated using bone cell culture using MC3T3-E1 osteoblast-like cells. The addition of strontium leads to enhanced proliferation suggesting the possible benefits of strontium incorporation in calcium phosphate coatings. The morphology and composition of deposited coatings showed a strong influence on the growth of cells.
在这项研究中，通过电化学沉积和等离子喷涂在不同的工艺参数下沉积了掺锶的磷酸钙涂层，以实现各种涂层形貌。通过能谱仪和 X 射线衍射研究了涂层的组成。通过扫描电子显微镜研究了涂层的表面形貌，同时使用 MC3T3-E1 成骨样细胞进行骨细胞培养来评估掺锶的磷酸钙涂层的细胞相容性和生物活性。锶的添加导致细胞增殖增强，表明锶掺入磷酸钙涂层可能具有益处。沉积涂层的形貌和组成对细胞的生长有很大的影响。
