Ebbesen P, Due C, Hesse J, Kurth R, Noble G R, Gallagher R, Voller A, Jensen G
Int J Cancer. 1979 Jul 15;24(1):1-5. doi: 10.1002/ijc.2910240102.
Untreated Danish Hodgkin's disease (HD) patients and paired age- and sex-matched controls were tested for serum antibodies to Epstein-Barr virus (EBV), six strains of influenza virus and Simian sarcoma virus/Simian sarcoma-associated virus [SSV(SSAV)] antigens. HD sera showed significantly elevated titers against EBV and both increased incidence and mean titer of antibodies to the envelope glycoprotein of SSV(SSAV), whereas testing against the influenza viruses revealed no differences between HD and controls. A focus reduction assay demonstrated a low incidence in HD and controls of sera with neutralizing effects against SSV(SSAV) and the "baboon" C-type virus component of the human HL-23 virus complex, which seemed coupled to HL-A type W19.
对未经治疗的丹麦霍奇金病（HD）患者以及年龄和性别匹配的对照者进行检测，以测定其血清中针对爱泼斯坦-巴尔病毒（EBV）、六种流感病毒株以及猿猴肉瘤病毒/猿猴肉瘤相关病毒[SSV(SSAV)]抗原的抗体。HD患者血清中针对EBV的滴度显著升高，并且针对SSV(SSAV)包膜糖蛋白的抗体发生率和平均滴度均有所增加，而针对流感病毒的检测显示HD患者与对照者之间没有差异。焦点减少试验表明，HD患者和对照者血清中对SSV(SSAV)以及人HL-23病毒复合体的“狒狒”C型病毒成分具有中和作用的发生率较低，这似乎与HL-A型W19相关。
