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无糖口香糖对社区中老年人的口腔健康和生活质量的潜在益处:一项随机对照试验。

The potential benefits of sugar-free chewing gum on the oral health and quality of life of older people living in the community: a randomized controlled trial.

机构信息

King's College London Dental Institute at Guy's, King's College and St Thomas's Hospitals, London, UK.

出版信息

Community Dent Oral Epidemiol. 2012 Oct;40(5):415-24. doi: 10.1111/j.1600-0528.2012.00685.x. Epub 2012 Apr 26.

Abstract

OBJECTIVES

To determine the effects of prescribing sugar-free chewing gum on the oral health and quality of life of dentate older people living in the community and attending for routine dental care.

METHODS

A randomized controlled trial was conducted on 186 older people who were not regular chewers of gum, (aged 60 years and over with ≥ 6 teeth) recruited from primary care clinics. Participants were randomly allocated to a gum-chewing group (chewing xylitol-containing gum twice a day for 15 min; n = 95) or a control group (no gum; n = 91). Both groups were examined at baseline and at the end of the study (6 months later). The primary outcome measure for the study was increased in stimulated saliva flow rate. Secondary measures included improvements in Plaque and Gingival Indices, and self-perceived change in oral health.

RESULTS

The retention rate for the study was 78.5% (n = 146 at follow-up); reported compliance with the protocol was 84% (ranged between 12% and 100%). There was no significant change in the saliva flow of the gum-chewing group (1.20-1.17 ml/min), while the control group experienced an increase in flow rate (1.06-1.32 ml/min; P = 0.001). The gum-chewing group, however, demonstrated significant improvement in Plaque and Gingival Index scores over the control group. For the Plaque Index, the mean scores (±SD) were 0.29 (±0.29) and 0.56 (±0.46) for the gum-chewing group and control groups, respectively (P < 0.001), at the second examination, which remained significant after controlling for age and saliva flow rate. For the Gingival Index, the scores were 0.73 (±0.30) and 0.92 (±0.32), respectively (P < 0.001), which persisted after controlling for age. A significantly higher proportion of participants in the gum-chewing group perceived that their oral health had improved during the study period in comparison with the control group (40% cf 21%; P = 0.016).

CONCLUSIONS

Prescription of sugar-free chewing gum to dentate older people living in the community and attending routine dental services was not associated with a significant increase in stimulated saliva flow. There were, however, significant improvements in Plaque and Gingival Index scores, and in self-perceived oral health.

摘要

目的

评估为社区中老年(≥ 6 颗牙齿且年龄在 60 岁及以上、非咀嚼口香糖习惯者)常规口腔护理患者开具无糖口香糖处方对其口腔健康和生活质量的影响。

方法

该研究采用随机对照试验设计,共纳入了 186 名中老年患者,这些患者均来自初级保健诊所,且不常咀嚼口香糖。参与者被随机分配至口香糖咀嚼组(每天咀嚼两次含有木糖醇的口香糖,每次 15 分钟;n = 95)或对照组(不咀嚼口香糖;n = 91)。两组均在基线和研究结束时(6 个月后)进行检查。研究的主要结局指标为唾液分泌率的增加。次要指标包括菌斑指数和牙龈指数的改善以及自我感知的口腔健康变化。

结果

研究的保留率为 78.5%(n = 146 名在随访时完成研究);报告的方案依从率为 84%(范围在 12%至 100%之间)。咀嚼口香糖组的唾液分泌率没有显著变化(1.20-1.17 ml/min),而对照组的唾液分泌率增加(1.06-1.32 ml/min;P = 0.001)。然而,与对照组相比,咀嚼口香糖组的菌斑指数和牙龈指数评分均有显著改善。在菌斑指数方面,咀嚼口香糖组和对照组的平均得分(±SD)分别为 0.29(±0.29)和 0.56(±0.46)(P < 0.001),第二次检查时差异仍然显著,且在控制年龄和唾液分泌率后仍有统计学意义。在牙龈指数方面,两组的得分分别为 0.73(±0.30)和 0.92(±0.32)(P < 0.001),且在控制年龄后差异仍然显著。与对照组相比,咀嚼口香糖组有更高比例的参与者在研究期间认为自己的口腔健康有所改善(40% vs 21%;P = 0.016)。

结论

为社区中老年常规口腔护理患者开具无糖口香糖处方与唾液分泌率的显著增加无关。然而,菌斑指数和牙龈指数评分以及自我感知的口腔健康均有显著改善。

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