2007-2008 年越南胡志明市自愿咨询检测点血浆和干血斑标本中传播的 HIV 耐药性监测。
Surveillance of transmitted HIV drug resistance using matched plasma and dried blood spot specimens from voluntary counseling and testing sites in Ho Chi Minh City, Vietnam, 2007-2008.
机构信息
Department of Health and Human Services/US Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
出版信息
Clin Infect Dis. 2012 May;54 Suppl 4(Suppl 4):S343-7. doi: 10.1093/cid/cir1049.
Abstract
During 2007-2008, surveillance of transmitted human immunodeficiency virus (HIV) drug resistance (TDR) was performed following World Health Organization guidance among clients with newly diagnosed HIV infection attending voluntary counseling and testing (VCT) sites in Ho Chi Minh City (HCMC), Vietnam. Moderate (5%-15%) TDR to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was observed among VCT clients aged 18-21 years. Follow-up surveillance of TDR in HCMC and other geographic regions of Vietnam is warranted. Data generated will guide the national HIV drug resistance surveillance strategy and support selection of current and future first-line antiretroviral therapy and HIV prevention programs.
摘要
2007-2008 年，根据世界卫生组织的指导，在越南胡志明市接受自愿咨询检测（VCT）服务的新诊断感染艾滋病毒的患者中，对传播的人类免疫缺陷病毒（HIV）耐药性（TDR）进行了监测。在年龄为 18-21 岁的 VCT 患者中，观察到中度（5%-15%）对非核苷类逆转录酶抑制剂（NNRTIs）的耐药性。有必要对胡志明市和越南其他地区的 TDR 进行后续监测。所产生的数据将指导国家 HIV 耐药性监测策略，并支持当前和未来一线抗逆转录病毒治疗和艾滋病毒预防方案的选择。
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