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青少年健康纵向研究中睡眠问题与自杀行为的前瞻性关系。

The prospective relationship between sleep problems and suicidal behavior in the National Longitudinal Study of Adolescent Health.

机构信息

Department of Psychology, Idaho State University, Pocatello, ID 83209-8112, USA.

出版信息

J Psychiatr Res. 2012 Jul;46(7):953-9. doi: 10.1016/j.jpsychires.2012.04.008. Epub 2012 May 1.

Abstract

OBJECTIVE

Previous research has found a longitudinal relationship between sleep problems and suicidal behavior while controlling for depression and other important covariates in a high risk sample of adolescents and controls. In this paper, we replicated this longitudinal relationship in a national sample and examined whether the relationship was partially mediated by depression, alcohol-related problems and other drug use.

METHODS

Study participants were 6504 adolescents from the National Longitudinal Study of Adolescent Health (ADD HEALTH).

RESULTS

In bivariate analyses, sleep problems (i.e., having trouble falling asleep or staying asleep) at Wave 1 were associated with suicidal thoughts and suicide attempts at Waves 1, 2, and 3 (W1, 2 and 3). In multivariate analyses, controlling for depression, alcohol problems, illicit drug use, and important covariates such as gender, age, and chronic health problems, sleep problems at a previous wave predicted suicidal thoughts and suicide attempts at a subsequent wave. In mediation analyses, W2 depression significantly mediated the effect of W1 sleep problems on W3 suicide thoughts. Moreover, W2 suicidal thoughts also significantly mediated the effect of W1 sleep problems on W3 suicidal attempts.

CONCLUSIONS

Sleep problems appear to be a robust predictor of subsequent suicidal thoughts and attempts in adolescence and young adulthood. Having trouble falling sleeping or staying asleep had both direct and indirect effects (via depression and suicidal thoughts) on suicidal behavior. Future research could determine if early intervention with sleep disturbances reduces the risk for suicidality in adolescents and young adults.

摘要

目的

在对青少年和对照组的高危样本进行抑郁和其他重要协变量控制后,先前的研究发现睡眠问题与自杀行为之间存在纵向关系。在本文中,我们在全国样本中复制了这种纵向关系,并检验了这种关系是否部分通过抑郁、与酒精相关的问题和其他药物使用来介导。

方法

研究参与者是来自国家青少年健康纵向研究(ADD HEALTH)的 6504 名青少年。

结果

在双变量分析中,第 1 波的睡眠问题(即入睡困难或保持睡眠)与第 1、2 和 3 波的自杀想法和自杀企图相关(W1、2 和 3)。在多变量分析中,控制抑郁、酒精问题、非法药物使用以及性别、年龄和慢性健康问题等重要协变量后,前一波的睡眠问题预测了随后一波的自杀想法和自杀企图。在中介分析中,W2 抑郁显著中介了 W1 睡眠问题对 W3 自杀想法的影响。此外,W2 自杀想法也显著中介了 W1 睡眠问题对 W3 自杀企图的影响。

结论

睡眠问题似乎是青少年和年轻成人随后自杀想法和企图的一个强有力的预测指标。入睡困难或保持睡眠既有直接影响(通过抑郁和自杀想法),也有间接影响(通过抑郁和自杀想法),对自杀行为有直接和间接影响。未来的研究可以确定早期干预睡眠障碍是否可以降低青少年和年轻成人自杀的风险。

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