Debert Iara, Polati Mariza, Jesus Daniela Lima de, Souza Eliane Cardoso dos Santos, Alves Milton Ruiz
Department of Ophthalmology, Universidade de São Paulo, Brazil.
Arq Bras Oftalmol. 2012 Jan-Feb;75(1):38-42.
To investigate the contribution of the individual ocular components, i.e. anterior chamber depth, lens thickness and vitreous chamber depth, to total axial length in patients with esotropic amblyopia.
The study population consisted of 74 children, aged between 5 and 8 years: thirty-seven patients with esotropic amblyopia and 37 healthy volunteers (control group). The participants underwent a comprehensive ophthalmological examination, including cycloplegic refraction and A-scan ultrasonography. Anterior chamber depth, lens thickness, vitreous chamber depth and total axial length were recorded. Paired Student's t-tests were used to compare biometric measurements between amblyopic eyes and their fellow eyes and between right and left eyes in the control group. To evaluate the contribution of the ocular components to the total axial length, we report the individual components as a percentage of total axial length.
The comparison between amblyopic and fellow eyes regarding the individual contribution from ocular components to the total axial length revealed greater contribution from lens thickness (P=0.001) and smaller contribution from vitreous chamber depth (P=0.001) in amblyopic eyes, despite similar contribution from anterior chamber depth (P=0.434). The comparison between right and left eyes in the control group showed similar contributions from anterior chamber depth (P=0.620), lens thickness (P=0.721), and vitreous chamber depth (P=0.483).
This study shows differences between amblyopic and non-amblyopic eyes when the total axial length is broken down into the individual contribution from the ocular components.
研究内斜视性弱视患者中，各个眼部组成部分，即前房深度、晶状体厚度和玻璃体腔深度，对眼轴总长度的影响。
研究对象为74名5至8岁的儿童，其中37名内斜视性弱视患者和37名健康志愿者（对照组）。参与者接受了全面的眼科检查，包括散瞳验光和A超超声检查。记录前房深度、晶状体厚度、玻璃体腔深度和眼轴总长度。采用配对t检验比较弱视眼与其对侧眼以及对照组左右眼之间的生物测量数据。为评估眼部组成部分对眼轴总长度的影响，我们将各个组成部分表示为眼轴总长度的百分比。
弱视眼与其对侧眼在眼部组成部分对眼轴总长度的个体贡献方面的比较显示，尽管前房深度的贡献相似（P = 0.434），但弱视眼中晶状体厚度的贡献更大（P = 0.001），而玻璃体腔深度的贡献更小（P = 0.001）。对照组左右眼之间的比较显示，前房深度（P = 0.620）、晶状体厚度（P = 0.721）和玻璃体腔深度（P = 0.483）的贡献相似。
本研究表明，当将眼轴总长度分解为各个眼部组成部分的个体贡献时，弱视眼与非弱视眼之间存在差异。
