Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.
BMC Ophthalmol. 2012 Sep 18;12:50. doi: 10.1186/1471-2415-12-50.
Ocular biometric parameters can be influenced by race, ethnicity, and genetics; their differences across different populations can probably explain differences in refractive errors in these populations. The aim of this study is to determine the normal range of axial length, anterior chamber depth, lens thickness, and vitreous chamber depth in the population of Shahroud in the north of Iran.
In the first phase of Shahroud Eye Cohort Study, the 40-64 year old population were sampled cross-sectionally; 6311 were invited and 5190 (82.2%) participated in the study. Biometric examinations were done using the LENSTAR/BioGraph (WaveLight AG, Erlangen, Germany) after vision tests and before cycloplegic refraction tests. Any type of eye surgery, extensive pterygium, and lack of cooperation were used as exclusion criteria, and analyses were done with data from 4869 eyes.
We found a mean axial length of 23.14 mm (95% confidence interval [CI], 23.11-23.17), mean anterior chamber depth of 2.62 mm (95% CI, 2.60-2.63), mean lens thickness of 4.28 mm (95% CI, 4.27-4.29), and the mean vitreous chamber depth was 15.72 mm (95% CI, 15.70-15.75).Kolmogorov-Smirnov tests showed that the distribution of axial length, anterior chamber depth, lens thickness, and vitreous chamber depth significantly differed from normal; axial length and vitreous chamber depth demonstrated a leptokurtic distribution as well.Axial length, anterior chamber depth, and vitreous chamber depth significantly decreased with age, and lens thickness significantly increased with age (p < 0.001). All indices were significantly higher in men.
The distributions of axial length, vitreous chamber depth, and lens thickness are reported for the first time in an Iranian adult population. Compared to other studies, axial length was in the mid range, nonetheless, studying axial length components showed that the Iranian population had smaller anterior chamber depth and lens thickness. Age and gender were significantly associated with all indices assessed in this study.
眼球生物测量参数受种族、民族和遗传因素的影响；不同人群之间的差异可能解释了这些人群中屈光不正的差异。本研究旨在确定伊朗北部沙拉武德地区人群的眼轴长度、前房深度、晶状体厚度和玻璃体腔深度的正常范围。
在沙拉武德眼部队列研究的第一阶段，采用横断面抽样方法对 40-64 岁人群进行抽样；邀请了 6311 人，其中 5190 人（82.2%）参加了研究。在视力测试后和睫状肌麻痹验光前，使用 LENSTAR/BioGraph（德国 Erlangen 的 WaveLight AG）进行生物测量检查。任何类型的眼部手术、广泛的翼状胬肉和缺乏合作都被用作排除标准，对 4869 只眼的数据进行了分析。
我们发现平均眼轴长度为 23.14mm（95%置信区间[CI]，23.11-23.17），平均前房深度为 2.62mm（95%CI，2.60-2.63），平均晶状体厚度为 4.28mm（95%CI，4.27-4.29），平均玻璃体腔深度为 15.72mm（95%CI，15.70-15.75）。柯尔莫哥洛夫-斯米尔诺夫检验显示，眼轴长度、前房深度、晶状体厚度和玻璃体腔深度的分布与正态分布显著不同；眼轴长度和玻璃体腔深度呈尖峰偏态分布。眼轴长度、前房深度和玻璃体腔深度随年龄增长而显著下降，晶状体厚度随年龄增长而显著增加（p<0.001）。所有指标在男性中均显著较高。
本研究首次报道了伊朗成年人眼轴长度、玻璃体腔深度和晶状体厚度的分布情况。与其他研究相比，眼轴长度处于中等范围，但研究眼轴长度组成部分表明，伊朗人群的前房深度和晶状体厚度较小。年龄和性别与本研究评估的所有指标均显著相关。
