Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
J Clin Microbiol. 2012 Jul;50(7):2513-4. doi: 10.1128/JCM.00590-12. Epub 2012 May 2.
Vancomycin-intermediate resistance has not been previously reported among sequence type 72 (ST72) methicillin-resistant Staphylococcus aureus (MRSA) isolates of SCCmec type IV (ST72-MRSA-IV), which are distinctive community genotype strains in Korea. We report the first case of vancomycin treatment failure due to development of vancomycin-intermediate resistance in infection caused by an ST72-MRSA-IV isolate.
先前并未报道过 72 型序列(ST72)耐甲氧西林金黄色葡萄球菌(MRSA)中万古霉素中介耐药性,而 72 型(ST72-MRSA-IV)的 SCCmec 型 IV 是韩国特有的社区基因型菌株。我们报告了首例因 ST72-MRSA-IV 分离株引起的感染而出现万古霉素中介耐药性导致万古霉素治疗失败的病例。