Servei de Patologia, Hospital Universitari Sant Joan de Reus, Reus-Tarragona, Spain.
Pathol Res Pract. 2012 Jun 15;208(6):368-71. doi: 10.1016/j.prp.2012.02.004. Epub 2012 May 1.
Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare neoplasm derived from antigen-presenting cells. IDCS displays aggressive behavior in a third of all cases, and the most common involvement is a solitary lymph node. We report the case of an 87-year-old woman with a right nasal mass. She underwent a wide local excision and right functional lymphadenectomy. Histopathological, immunohistochemical and molecular studies were consistent with the diagnosis of IDCS. Although it is extremely rare, this case suggests that extranodal IDCS should be considered in the differential diagnosis of undifferentiated fusiform neoplasms.
指状突树突细胞肉瘤（IDCS）是一种源自抗原呈递细胞的极为罕见的肿瘤。IDCS 在所有病例中有三分之一表现出侵袭性行为，最常见的受累部位是单个淋巴结。我们报告了一例 87 岁女性右侧鼻腔肿块。她接受了广泛的局部切除和右侧功能性淋巴结清扫术。组织病理学、免疫组织化学和分子研究与 IDCS 的诊断一致。尽管这种情况极为罕见，但本例提示在鉴别诊断未分化梭形肿瘤时应考虑结外 IDCS。
