Lee Eun Jung, Hyun Dong Woo, Cho Hyung-Ju, Lee Jeung-Gweon
Department of Otolaryngology-Head and Neck Surgery, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, Republic of Korea.
Case Rep Otolaryngol. 2013;2013:913157. doi: 10.1155/2013/913157. Epub 2013 Apr 21.
Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare neoplasm that mainly arises from the lymphoid tissues of the immune system. Although this neoplasm typically occurs anywhere along the lymph nodes, it can also be found at extranodal sites, especially in the head and neck. We experienced a rare case of extranodal IDCS in the nasal cavity, a location that has not been previously reported. A 73-year-old woman presented with a polyp-like mass in the nasal cavity and underwent endoscopic sinus surgery. A histologic study confirmed the mass as IDCS by immunohistochemistry with S-100 antibody, and postoperative adjuvant radiotherapy was administered. Although the incidence is extremely rare, this case suggests that extranodal IDCS should be considered in the differential diagnosis of nasal cavity masses.
交错突树突状细胞肉瘤（IDCS）是一种极为罕见的肿瘤，主要起源于免疫系统的淋巴组织。尽管这种肿瘤通常发生在沿淋巴结的任何部位，但也可在结外部位发现，尤其是头颈部。我们遇到了一例罕见的鼻腔结外IDCS病例，该部位此前未见报道。一名73岁女性因鼻腔内息肉样肿物就诊并接受了鼻内镜鼻窦手术。组织学研究通过S-100抗体免疫组化确诊该肿物为IDCS，并进行了术后辅助放疗。尽管发病率极低，但该病例提示在鼻腔肿物的鉴别诊断中应考虑结外IDCS。
