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黄果茄浆果对雄性大鼠的避孕效果。

Contraceptive efficacy of solanum xanthocarpum berry in male rats.

作者信息

Purohit A

机构信息

Reproduction Physiology Section, Department of Zoology, Birla College, Kalyan - 421 304, India.

出版信息

Anc Sci Life. 1992 Jul;12(1-2):264-6.

PMID:22556599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3336623/
Abstract

Oral feeding of 50% EtOH of Solanum xanthocarpum berry to male rats at the dose of 0.5 gm/kg body weight caused arrest of spermotagenesis. The number of spermatocytes (primary and secondary) and spermatids were significantly reduced (P<0.05 to 0.001). The total number of immature and mature leydig cells were significantly decreased (P<0.001), whereas degenerating cells were significantly increased (P<0.001). The decreased testicular cell population reflects antispermatogenic nature of Solanium xanthocarpum berry extract.

摘要

以0.5克/千克体重的剂量给雄性大鼠经口投喂黄果茄浆果的50%乙醇提取物,会导致精子发生停滞。精母细胞(初级和次级)和精子细胞的数量显著减少(P<0.05至0.001)。未成熟和成熟的莱迪希细胞总数显著减少(P<0.001),而退化细胞显著增加(P<0.001)。睾丸细胞数量的减少反映了黄果茄浆果提取物的抗精子发生特性。

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