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1
'Antiandrogenic properties of neem seed oil (azadirachta indica) in male rat and rabbi'.印楝籽油(印楝)对雄性大鼠和兔子的抗雄激素特性
Anc Sci Life. 1987 Jul;7(1):30-8.
2
Effect of aqueous leaf extract of Azadirachta indica on the reproductive organs in male mice.印楝叶水提取物对雄性小鼠生殖器官的影响。
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3
Treatment with Azadirachta indica in diabetic pregnant rats: negative effects on maternal outcome.在糖尿病妊娠大鼠中使用印苦楝治疗:对母体结局的负面影响。
J Ethnopharmacol. 2012 Oct 11;143(3):805-11. doi: 10.1016/j.jep.2012.07.023. Epub 2012 Aug 15.
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Azadirachta indica treatment on the congenital malformations of fetuses from rats.印楝处理对大鼠胎儿先天畸形的影响。
J Ethnopharmacol. 2013 Dec 12;150(3):1109-13. doi: 10.1016/j.jep.2013.10.046. Epub 2013 Oct 31.
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Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats.印度楝树皮(Azadirachta indica A.juss.)对雄性大鼠的抗生育功效
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Effects of graded levels of Azadirachta indica seed oil on growth performance and biochemical profiles of broiler chickens.印楝籽油不同梯度水平对肉鸡生长性能和生化指标的影响。
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Antifertility effects of neem (Azadirachta indica) oil in male rats by single intra-vas administration: an alternate approach to vasectomy.
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Ultrastructural changes in Leydig cells and cauda epididymal spermatozoa induced by Azadirachta indica leaves in albino rats.印楝叶对白化大鼠睾丸间质细胞和附睾尾部精子超微结构的影响
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Ultrastructural changes induced by leaves of Azadirachta indica (Neem) in the testis of albino rats.印度楝树叶对白化大鼠睾丸诱导产生的超微结构变化。
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Acute toxicity study of the oil from Azadirachta indica seed (neem oil).印楝种子油(印楝油)的急性毒性研究。
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引用本文的文献

1
A Critical Review and Scientific Prospective on Contraceptive Therapeutics from Ayurveda and Allied Ancient Knowledge.对阿育吠陀及相关古代知识中避孕疗法的批判性综述与科学展望。
Front Pharmacol. 2021 Jun 3;12:629591. doi: 10.3389/fphar.2021.629591. eCollection 2021.

印楝籽油(印楝)对雄性大鼠和兔子的抗雄激素特性

'Antiandrogenic properties of neem seed oil (azadirachta indica) in male rat and rabbi'.

作者信息

Sharma J D, Jha R K, Gupta I, Jain P, Dixit V P

机构信息

Reproductive Physiology Unit, Department of Zooloogy, University of Rajasthan, Jaipur - 302 004, India.

出版信息

Anc Sci Life. 1987 Jul;7(1):30-8.

PMID:22557585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3331377/
Abstract

Azadirachta indica (Neem) seed oil brings about a significant diminution in spermatozoan motility and density. It leads to reduction of fertility rate in rats and rabbits. The body weight of the animals remain unaffected but the weights of reproductive oranges declined. Reduction of cauda epididymal protein, sialic acid, acid phosphatase and seminal vesicular fructose concentration in rats and rabbits could bedue to antiandrogenic action of the seed oil as confirmed with the help of bioassay techniques. Histopathology of testis revealed arrest of spermatogenesis and sever degenerative changes in the cauda epididymis.

摘要

印楝(楝树)籽油会导致精子活力和密度显著降低。它会使大鼠和兔子的生育率下降。动物的体重未受影响,但生殖器官的重量有所下降。大鼠和兔子附睾尾部蛋白质、唾液酸、酸性磷酸酶以及精囊果糖浓度的降低,可能归因于该籽油的抗雄激素作用,这已通过生物测定技术得到证实。睾丸组织病理学显示精子发生停滞,附睾尾部出现严重退行性变化。