Purohit A
Reproductive Physiology Section, Department of Zoology, J.N.V. University, Jodhpur - 342 005, India.
Anc Sci Life. 1999 Jul;19(1-2):21-4.
Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ protein, sialic acid and vesicular fructose content manifested arrest of spermatogenesis and depletion of androgen level.
以10毫克的剂量对雄性大鼠进行印楝树皮（印楝）50%乙醇提取物的皮下给药，持续30天，导致精子发生停滞。曲细精管直径、睾丸间质细胞核以及附睾上皮高度均显著减小（p≤0.001）。精子活力和密度显著降低。睾丸及附属器官蛋白质、唾液酸和囊泡果糖含量减少，表明精子发生停滞以及雄激素水平降低。
