School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, New South Wales, Australia.
Med Phys. 2012 May;39(5):2839-47. doi: 10.1118/1.4709602.
To investigate the properties of a modified backscatter shielded electronic portal imaging device (BSS-EPID) and to develop a dose model to convert BSS-EPID images to dose in water as part of an improved system for dosimetry using EPIDs.
The effectiveness of the shielding of the BSS-EPID was studied by comparing images measured with the BSS-EPID mounted on the support arm to images measured with the BSS-EPID removed from the support arm. A dose model was developed and optimized to reconstruct dose in water at different depths from measured BSS-EPID images. The accuracy of the dose model was studied using BSS-EPID images of 28 IMRT fields to reconstruct dose in water at depths of 2, 5, 10, and 20 cm and comparing to measured dose in water from a two-dimensional diode array at the same depths. The ability of the BSS-EPID system to operate independently of detector position was demonstrated by comparing the dose reconstruction of a 10 × 10 cm(2) field using different detector offsets to that measured by a two-dimensional diode array.
The shielding of the BSS-EPID was found to be effective, with more than 99% of pixels showing less than 0.5% change due to the presence of the support arm and at most a 0.2% effect on the central axis for 2 × 2 cm(2) fields to fully open 30 × 40 cm(2) images. The dose model was shown to accurately reconstruct measurements of dose in water using BSS-EPID images with average γ pass rates (2%, 2 mm criteria) of 92.5%, 98.7%, 97.4%, and 97.2% at depths of 2, 5, 10, and 20 cm, respectively, when compared to two-dimensional diode array measurements. When using 3%, 3 mm γ criteria, the average pass rate was greater than 97% at all depths. Reconstructed dose in water for a 10 × 10 cm(2) field measured with detector offsets as large as 10 cm agreed with each other and two-dimensional diode array measurements within 0.9%.
The modified BSS-EPID and associated dose model provide an improved system for dosimetry measurements using EPIDs. Several important limitations of the current hardware and software are addressed by this system.
研究一种改良型背散射屏蔽电子射野影像装置(BSS-EPID)的特性,并开发一种剂量模型,以便将 BSS-EPID 图像转换为水中的剂量,作为 EPID 剂量测量系统的改进。
通过比较安装在支撑臂上的 BSS-EPID 测量的图像和从支撑臂上移除的 BSS-EPID 测量的图像,研究 BSS-EPID 的屏蔽效果。开发并优化了一种剂量模型,以便从测量的 BSS-EPID 图像中重建不同深度的水中剂量。使用 28 个调强放射治疗场的 BSS-EPID 图像,研究剂量模型的准确性,以重建 2、5、10 和 20 cm 深度的水中剂量,并与二维二极管阵列在相同深度测量的水中剂量进行比较。通过比较不同探测器偏移量对 10×10 cm² 射野的剂量重建与二维二极管阵列的测量结果,证明 BSS-EPID 系统能够独立于探测器位置运行。
发现 BSS-EPID 的屏蔽效果非常有效,超过 99%的像素由于支撑臂的存在而显示出小于 0.5%的变化,对于 2×2 cm² 射野,中央轴的最大影响为 0.2%,可完全打开 30×40 cm² 的图像。剂量模型能够准确地重建 BSS-EPID 图像测量的水中剂量,当与二维二极管阵列的测量结果相比时,在 2、5、10 和 20 cm 的深度处,平均 γ 通过率(2%,2 mm 标准)分别为 92.5%、98.7%、97.4%和 97.2%。当使用 3%、3 mm γ 标准时,所有深度的平均通过率均大于 97%。对于最大偏移量为 10 cm 的探测器测量的 10×10 cm² 射野的重建水中剂量,与彼此以及二维二极管阵列的测量结果在 0.9%以内一致。
改良的 BSS-EPID 和相关的剂量模型为 EPID 剂量测量提供了一种改进的系统。该系统解决了当前硬件和软件的几个重要限制。