Zhang Jun, Fan Ziting, Zhang Xile, Yang Ruijie, Wen Junhai
Department of Biomedical Engineering, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China.
Diagnostics (Basel). 2021 Sep 9;11(9):1654. doi: 10.3390/diagnostics11091654.
Support arm backscatter and off-axis effects of an electronic portal imaging device (EPID) are challenging for radiotherapy quality assurance. Aiming at the issue, we proposed a simple yet effective method with correction matrices to rectify backscatter and off-axis responses for EPID images. First, we measured the square fields with ionization chamber array (ICA) and EPID simultaneously. Second, we calculated the dose-to-pixel value ratio and used it as the correction matrix of the corresponding field. Third, the correction value of the large field was replaced with that of the same point in the small field to generate a correction matrix suitable for different EPID images. Finally, we rectified the EPID image with the correction matrix, and then the processed EPID images were converted into the absolute dose. The calculated dose was compared with the measured dose via ICA. The gamma pass rates of 3%/3 mm and 2%/2 mm (5% threshold) were 99.6% ± 0.94% and 95.48% ± 1.03%, and the average gamma values were 0.28 ± 0.04 and 0.42 ± 0.05, respectively. Experimental results verified our method accurately corrected EPID images and converted pixel values into absolute dose values such that EPID was an efficient radiotherapy dosimetry tool.
电子射野影像装置(EPID)的支撑臂背散射和离轴效应给放射治疗质量保证带来了挑战。针对这一问题,我们提出了一种简单而有效的方法,使用校正矩阵来校正EPID图像的背散射和离轴响应。首先,我们同时使用电离室阵列(ICA)和EPID测量方形射野。其次,我们计算剂量与像素值的比值,并将其用作相应射野的校正矩阵。第三,将大射野的校正值替换为小射野中同一点的校正值,以生成适用于不同EPID图像的校正矩阵。最后,我们用校正矩阵校正EPID图像,然后将处理后的EPID图像转换为绝对剂量。通过ICA将计算得到的剂量与测量剂量进行比较。3%/3mm和2%/2mm(5%阈值)的伽马通过率分别为99.6%±0.94%和95.48%±1.03%,平均伽马值分别为0.28±0.04和0.42±0.05。实验结果验证了我们的方法能够准确校正EPID图像,并将像素值转换为绝对剂量值,从而使EPID成为一种有效的放射治疗剂量测定工具。