Department of Dermatology, Duke University Medical Center, Durham, NC 27710, USA.
Immunol Allergy Clin North Am. 2012 May;32(2):275-81, vi-vii. doi: 10.1016/j.iac.2012.04.007. Epub 2012 Apr 18.
The major treatment strategies for DH are gluten restriction or medical treatment with sulfones. Control of the cutaneous manifestations, but not the gastrointestinal changes, is rapid with dapsone. In addition to control of the cutaneous signs and symptoms of DH, dietary gluten restriction also induces improvement of gastrointestinal morphology and is possibly protective against the development of lymphoma.
DH 的主要治疗策略是限制 gluten 摄入或使用磺胺类药物进行医学治疗。达普司酮能迅速控制皮肤表现,但不能控制胃肠道变化。除了控制 DH 的皮肤症状外,限制 gluten 摄入还能改善胃肠道形态,并可能预防淋巴瘤的发展。