Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 78 Saemoonan-gil, Jongno-gu, Seoul 110-746, Republic of Korea.
Trans R Soc Trop Med Hyg. 2012 Jul;106(7):429-36. doi: 10.1016/j.trstmh.2012.03.011. Epub 2012 May 4.
The number of Plasmodium vivax malaria cases in the Republic of Korea (ROK) in 2008 was 1009, a 54.2% decrease on the previous year. It then resurged to 1317 cases in 2009 (30.5% increase on 2008). One possible cause for the sharp decrease in 2008 might be the large-scale presumptive anti-relapse therapy with primaquine that was undertaken in the Democratic People's Republic of Korea in 2007. Of the 2326 cases of P. vivax malaria diagnosed in the ROK during 2008-2009, 599 cases (25.8%) were military personnel, 535 cases (23.0%) were veterans, and 1192 cases (51.2%) were civilians. Local transmission within the ROK appeared to increase gradually, and the length of the transmission period of P. vivax malaria extended during this period. Parasite clearance time after chloroquine treatment has increased in the late 2000s, which requires the introduction of countermeasures against the decreasing chloroquine susceptibility, including reduction of mass chemoprophylaxis with chloroquine in the ROK Army.
2008 年韩国（ROK）间日疟病例数为 1009 例，比前一年减少 54.2%。随后在 2009 年又回升至 1317 例（比 2008 年增加 30.5%）。2008 年病例数大幅下降的一个可能原因是 2007 年朝鲜民主主义人民共和国大规模开展了以伯氨喹进行的抗复发治疗。在 2008-2009 年期间，韩国共诊断出 2326 例间日疟病例，其中 599 例（25.8%）为军人，535 例（23.0%）为退伍军人，1192 例（51.2%）为平民。韩国境内的本地传播似乎逐渐增加，间日疟传播期也延长。2000 年代后期，氯喹治疗后的寄生虫清除时间增加，这需要采取措施应对氯喹敏感性降低的问题，包括减少韩国陆军大规模使用氯喹进行化学预防。
