Department of Haematology, Roald Dahl Haemostasis and Thrombosis Centre, Royal Liverpool University Hospital, Liverpool L7 8XP, United Kingdom.
Blood Rev. 2012 Jul;26(4):175-81. doi: 10.1016/j.blre.2012.04.002. Epub 2012 May 2.
There has been immense progress in the management of venous thromboembolism in recent years with increased awareness and adequate thromboprophylaxis proving successful in reducing the morbidity and mortality associated with this condition. One of the commonest complications of an initial venous thrombosis is the development of recurrent thrombosis. Unlike in the case of the first clot, the diagnosis and management of the recurrent episode remain a difficult issue. Even more challenging is the clinical situation where a new thrombus develops while the patient is being treated with anticoagulant medication for a previous clot. The clinical approach and management of these patients are complex, and require understanding of the differences in thrombus development in the different clinical circumstances.
近年来，静脉血栓栓塞症的管理取得了巨大进展，通过提高认识和充分的血栓预防，成功降低了与该疾病相关的发病率和死亡率。初始静脉血栓形成的最常见并发症之一是复发性血栓形成。与首次血栓形成不同，复发性血栓形成的诊断和管理仍然是一个难题。更具挑战性的是，在患者因前一次血栓形成而接受抗凝药物治疗的情况下，新的血栓形成。这些患者的临床处理和管理很复杂，需要了解不同临床情况下血栓形成的差异。
