Department of Psychiatry (966), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
J Autism Dev Disord. 2013 Jan;43(1):45-56. doi: 10.1007/s10803-012-1546-4.
It is unclear whether symptoms of autism spectrum disorder (ASD) in young children in the population fit the three-factor structure of ASD as described in the DSM-IV, and cluster together in individual subjects. This study analysed questionnaire data on ASD symptoms filled in by mothers of 11,332 18-month-old children that was collected in the context of the Norwegian Mother and Child Cohort Study conducted by the Norwegian Institute of Public Health. Confirmatory Factor Analyses showed that the three-factor model had a significantly better fit then the two- and one-factor model of ASD symptoms. Latent class analysis revealed four homogeneous groups of children (classes) with different scores for Social Interaction and Communication at one hand and Stereotypies/Rigidity at the other hand.
目前尚不清楚人群中幼儿自闭症谱系障碍（ASD）的症状是否符合 DSM-IV 中描述的 ASD 的三因素结构，并且是否在个体受试者中聚集在一起。本研究分析了挪威公共卫生研究所进行的挪威母婴队列研究中 11332 名 18 个月大的儿童的母亲填写的自闭症谱系障碍症状问卷数据。验证性因子分析表明，三因素模型比 ASD 症状的两因素和一因素模型具有更好的拟合度。潜在类别分析显示，儿童（类别）在社会互动和沟通方面的得分以及刻板行为/僵化性方面的得分存在四个具有不同特征的同质群体。
