Department of Internal Medicine, Inje University College of Medicine, Goyang, Korea.
J Korean Med Sci. 2012 May;27(5):518-24. doi: 10.3346/jkms.2012.27.5.518. Epub 2012 Apr 25.
The purpose of this study was to investigate the stage of glucose intolerance in which persons showed a maximum obesity in Korea. A total of 4,479 participants, who were involved in the 2005 Korean National Health and Nutrition Examination Survey, was examined. The participants were divided into 5 groups by fasting plasma glucose (FPG); normal fasting glucose (NFG)1, FPG < 90 mg/dL; NFG2, FPG 90-99 mg/dL; impaired fasting glucose (IFG)1, FPG 100-109 mg/dL; IFG2, FPG 110-125 mg/dL; and diabetes mellitus, FPG ≥ 126 mg/dL or with anti-diabetes drugs. In those with FPG < 110 mg/dL, body mass index (BMI) and waist circumference (WC) were increased with increase of FPG (BMI in men; NFG1, 23.3 ± 0.1; NFG2, 24.4 ± 0.1; IFG1, 25.0 ± 0.2 kg/m(2), in women; NFG1, 23.0 ± 0.1; NFG2, 24.0 ± 0.1; IFG1, 24.8 ± 0.2 kg/m(2), WC in men; NFG1, 82.1 ± 0.3; NFG2, 85.3 ± 0.3; IFG1, 86.7 ± 0.5 cm, in women; NFG1, 77.1 ± 0.2; NFG2, 79.4 ± 0.3; IFG1, 81.8 ± 0.6 cm). In IFG2 and diabetes range, there was no more increase of BMI and WC with increase of FPG in each sex. The data suggest that degree of obesity increases with an increase of FPG in range of FPG < 100 mg/dL, peaked in FPG of 100-109 mg/dL, and then plateaus in higher FPG range in general Korean population.
本研究旨在探讨韩国人群中葡萄糖耐量受损阶段的肥胖程度。共纳入 2005 年韩国国家健康和营养调查的 4479 名参与者。根据空腹血糖（FPG）将参与者分为 5 组：正常空腹血糖（NFG）1，FPG＜90mg/dL；NFG2，FPG 90-99mg/dL；空腹血糖受损（IFG）1，FPG 100-109mg/dL；IFG2，FPG 110-125mg/dL；糖尿病，FPG≥126mg/dL 或使用抗糖尿病药物。在 FPG＜110mg/dL 的人群中，随着 FPG 的升高，体重指数（BMI）和腰围（WC）增加（男性：NFG1，23.3±0.1；NFG2，24.4±0.1；IFG1，25.0±0.2kg/m²；女性：NFG1，23.0±0.1；NFG2，24.0±0.1；IFG1，24.8±0.2kg/m²；男性：NFG1，82.1±0.3；NFG2，85.3±0.3；IFG1，86.7±0.5cm；女性：NFG1，77.1±0.2；NFG2，79.4±0.3；IFG1，81.8±0.6cm）。在 IFG2 和糖尿病范围内，男女两性 FPG 升高时 BMI 和 WC 无进一步增加。数据表明，在 FPG＜100mg/dL 范围内，FPG 升高与肥胖程度增加相关，在 FPG 100-109mg/dL 时达到峰值，随后在普通韩国人群的较高 FPG 范围内趋于平稳。
