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1
Human adjuvant disease: remission of silicone induced autoimmune disease after explanation of breast augmentation.人类佐剂病：隆胸假体取出后硅酮诱导的自身免疫性疾病缓解
Ann Rheum Dis. 1990 Nov;49(11):937-8. doi: 10.1136/ard.49.11.937.
2
Human adjuvant disease, possible autoimmune disease after silicone implantation: a review of the literature, case studies, and speculation for the future.人类佐剂病，硅胶植入后可能出现的自身免疫性疾病：文献综述、病例研究及对未来的推测
Plast Reconstr Surg. 1986 Jul;78(1):104-14. doi: 10.1097/00006534-198607000-00018.
3
Do silicone breast implants cause autoimmune rheumatic diseases?硅胶乳房植入物会引发自身免疫性风湿疾病吗？
J Biomater Sci Polym Ed. 1995;7(2):115-21. doi: 10.1163/156856295x00634.
4
[Does silicone induce autoimmune diseases? Review of the literature and case reports].[硅酮会引发自身免疫性疾病吗？文献综述与病例报告]
Z Rheumatol. 1992 Jan-Feb;51(1):31-4.
5
Antinuclear autoantibodies in women with silicone breast implants.患有硅胶乳房植入物的女性体内的抗核自身抗体。
Lancet. 1992 Nov 28;340(8831):1304-7. doi: 10.1016/0140-6736(92)92491-w.
6
Silicone breast implants and immune disease.
Ann Plast Surg. 1992 May;28(5):491-9; discussion 499-501. doi: 10.1097/00000637-199205000-00017.
7
[Silicone breast prosthesis and rheumatoid arthritis: a new systemic disease: siliconosis. A case report and a critical review of the literature].[硅胶乳房假体与类风湿性关节炎：一种新的全身性疾病：硅肺病。病例报告及文献综述]
Minerva Med. 1998 Apr;89(4):117-30.
8
[Late reactions following implantation of silicone prostheses].[硅胶假体植入后的迟发反应]
Urologe A. 1991 Sep;30(5):302-5.
9
[Silicone breast implants and collagen diseases].
Tidsskr Nor Laegeforen. 1992 Feb 28;112(6):763-4.
10
A case of malignant hypertension and scleroderma after cosmetic surgery.一例整容手术后出现恶性高血压和硬皮病的病例。
Jpn J Med. 1991 Jan-Feb;30(1):97-100. doi: 10.2169/internalmedicine1962.30.97.

引用本文的文献

1
The Prevalence of Hearing Impairments in Women with Silicone Breast Implants.硅胶乳房植入女性中听力障碍的患病率。
Diseases. 2023 Feb 9;11(1):31. doi: 10.3390/diseases11010031.
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Development of Lobular Panniculitis Long After Completing the Personalized Peptide Vaccine Therapy.完成个性化肽疫苗治疗很久之后发生的小叶性脂膜炎
Am J Case Rep. 2018 Dec 27;19:1530-1535. doi: 10.12659/AJCR.912418.
3
ASIA syndrome, calcinosis cutis and chronic kidney disease following silicone injections. A case-based review.硅注射后出现的亚洲综合征、皮肤钙质沉着和慢性肾病。基于病例的综述。
Immunol Res. 2016 Dec;64(5-6):1142-1149. doi: 10.1007/s12026-016-8871-1.
4
Intravascular large B-cell lymphoma associated with silicone breast implant, HLA-DRB1*11:01, and HLA-DQB1*03:01 manifesting as macrophage activation syndrome and with severe neurological symptoms: a case report.与硅胶乳房植入物、HLA-DRB1*11:01和HLA-DQB1*03:01相关的血管内大B细胞淋巴瘤表现为巨噬细胞活化综合征并伴有严重神经症状：一例报告
J Med Case Rep. 2016 Sep 15;10(1):254. doi: 10.1186/s13256-016-0993-5.
5
Autoimmune/inflammatory syndrome induced by adjuvant (ASIA) evolution after silicone implants. Who is at risk?硅胶植入后佐剂诱导的自身免疫/炎症综合征（ASIA）的演变。哪些人有风险？
Clin Rheumatol. 2015 Oct;34(10):1661-6. doi: 10.1007/s10067-015-2931-0. Epub 2015 Apr 16.
6
[Serious complications following gluteal injection of silicone].[臀肌注射硅酮后的严重并发症]
Hautarzt. 2013 Aug;64(8):599-602. doi: 10.1007/s00105-013-2573-6.
7
The immunopathology of siliconosis. History, clinical presentation, and relation to silicosis and the chemistry of silicon and silicone.矽肺的免疫病理学。历史、临床表现以及与矽肺的关系和硅与硅氧烷的化学性质。
Immunol Res. 1998;18(3):125-73. doi: 10.1007/BF02788777.

本文引用的文献

1
Adjuvant effect of silica (tridymite) on antibody production.二氧化硅（鳞石英）对抗体产生的佐剂效应。
Proc Soc Exp Biol Med. 1962 Jun;110:390-2. doi: 10.3181/00379727-110-27527.
2
Development of arthritis, periarthritis and periostitis in rats given adjuvants.给予佐剂的大鼠关节炎、关节周围炎和骨膜炎的发展。
Proc Soc Exp Biol Med. 1956 Jan;91(1):95-101. doi: 10.3181/00379727-91-22179.
3
Post-mammoplasty connective tissue disease.乳房成形术后结缔组织病
Arthritis Rheum. 1982 Jun;25(6):694-7. doi: 10.1002/art.1780250613.
4
Silicone-induced human adjuvant disease?
Ann Plast Surg. 1983 Apr;10(4):270-3. doi: 10.1097/00000637-198304000-00002.
5
Acute pneumonitis after subcutaneous injections of silicone in transsexual men.
N Engl J Med. 1983 Mar 31;308(13):764-7. doi: 10.1056/NEJM198303313081307.
6
Scleroderma, primary biliary cirrhosis, and Sjögren's syndrome after cosmetic breast augmentation with silicone injection: a case report of possible human adjuvant disease.硅胶注射隆乳术后出现硬皮病、原发性胆汁性肝硬化和干燥综合征：一例可能的人类佐剂病病例报告
Ann Rheum Dis. 1984 Jun;43(3):520-2. doi: 10.1136/ard.43.3.520.
7
Autoimmune disease developing after augmentation mammoplasty: report of 3 cases.隆乳术后发生的自身免疫性疾病：3例报告。
J Rheumatol. 1984 Feb;11(1):98-100.
8
Capsular contracture in silicone gel and saline-filled breast implants after reconstruction.乳房重建后硅胶和盐水填充乳房植入物中的包膜挛缩。
Plast Reconstr Surg. 1984 Feb;73(2):270-5. doi: 10.1097/00006534-198402000-00022.
9
Clinical spectrum of connective tissue disease after cosmetic surgery. Observations on eighteen patients and a review of the Japanese literature.美容手术后结缔组织疾病的临床谱。18例患者的观察及日本文献综述。
Arthritis Rheum. 1984 Jan;27(1):1-12. doi: 10.1002/art.1780270101.
10
Hypercalcemia associated with silicone-induced granulomas.
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人类佐剂病：隆胸假体取出后硅酮诱导的自身免疫性疾病缓解

Human adjuvant disease: remission of silicone induced autoimmune disease after explanation of breast augmentation.

作者信息

kaiser W, Biesenbach G, Stuby U, Grafinger P, Zazgornik J

机构信息

IInd Medical Department, General Hospital Linz, Austria.

出版信息

Ann Rheum Dis. 1990 Nov;49(11):937-8. doi: 10.1136/ard.49.11.937.

DOI:10.1136/ard.49.11.937
PMID:2256743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1004268/
Abstract

Autoimmune diseases following silicone or paraffin implantation are rarely encountered complications of plastic surgery. A 42 year old woman is presented who developed clinical and immunological features of systemic lupus erythematosus 11 years after silicone augmentation. After explanation antinuclear antibody titres decreased from 1/1280 to 1/160, C4 complement fraction and the previously raised angiotensin converting enzyme normalised in step with clinical improvement. It is important that plastic surgeons and rheumatologists should be aware of this possible association.

摘要

硅胶或石蜡植入后引发的自身免疫性疾病是整形外科中罕见的并发症。本文报告了一名42岁女性，她在硅胶隆乳11年后出现了系统性红斑狼疮的临床和免疫学特征。经解释后，抗核抗体滴度从1/1280降至1/160，C4补体成分以及先前升高的血管紧张素转换酶随着临床症状的改善而恢复正常。整形外科医生和风湿病学家应意识到这种可能的关联，这一点很重要。