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肾脏中的新型感觉信号系统。

Novel sensory signaling systems in the kidney.

机构信息

Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Curr Opin Nephrol Hypertens. 2012 Jul;21(4):404-9. doi: 10.1097/MNH.0b013e328354a6bd.

DOI:10.1097/MNH.0b013e328354a6bd
PMID:22569342
Abstract

PURPOSE OF REVIEW

This review summarizes recent literature highlighting the roles of chemical and mechanical sensory receptors in renal function.

RECENT FINDINGS

Both chemoreceptors and mechanoreceptors play important roles in renal physiology; here, we discuss specific examples of both chemoreceptors and mechanoreceptors in the kidney.

SUMMARY

In order to maintain homeostasis, the kidney uses sensory receptors to assess the composition and rate of flow of the forming urine. Understanding the roles of these receptors will help us to better understand how the kidney functions both in health and in disease.

摘要

目的综述

本文综述了近期文献,强调了化学和机械感觉受体在肾功能中的作用。

最近的发现

化学感受器和机械感受器在肾脏生理中都起着重要作用;在这里,我们讨论了肾脏中化学感受器和机械感受器的具体例子。

总结

为了维持体内平衡,肾脏利用感觉受体来评估形成尿液的成分和流速。了解这些受体的作用将有助于我们更好地理解肾脏在健康和疾病中的功能。

相似文献

1
Novel sensory signaling systems in the kidney.肾脏中的新型感觉信号系统。
Curr Opin Nephrol Hypertens. 2012 Jul;21(4):404-9. doi: 10.1097/MNH.0b013e328354a6bd.
2
Electrophysiology of afferent renal nerves.肾传入神经的电生理学
Fed Proc. 1985 Oct;44(13):2828-33.
3
Roles of gastro-oesophageal afferents in the mechanisms and symptoms of reflux disease.胃食管传入神经在反流性疾病的机制和症状中的作用。
Handb Exp Pharmacol. 2009(194):227-57. doi: 10.1007/978-3-540-79090-7_7.
4
Electrophysiological characteristics of renal sensory receptors and afferent renal nerves.肾感觉受体和肾传入神经的电生理特征。
Miner Electrolyte Metab. 1989;15(1-2):59-65.
5
[Observation on the afferent nerve activity induced by stimulation of renal receptors in the rabbits].[刺激家兔肾感受器诱发传入神经活动的观察]
Sheng Li Xue Bao. 1990 Jun;42(3):269-76.
6
Interactions between the sympathetic nervous system and the kidney: experimental observations.交感神经系统与肾脏之间的相互作用:实验观察
J Hypertens Suppl. 1985 Dec;3(4):S19-25.
7
Renorenal reflexes: neural and functional responses.肾-肾反射:神经及功能反应
Fed Proc. 1985 Oct;44(13):2834-9.
8
Transient receptor potential cation channels in visceral sensory pathways.内脏感觉通路中的瞬时受体电位阳离子通道。
Br J Pharmacol. 2014 May;171(10):2528-36. doi: 10.1111/bph.12641.
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Differentiation of papillae and rostral sensory neurons in the larva of the ascidian Botryllus schlosseri (Tunicata).海鞘幼虫(Botryllus schlosseri)的乳突和吻感觉神经元的分化(苔虫动物门)。
J Comp Neurol. 2010 Feb 15;518(4):547-66. doi: 10.1002/cne.22222.
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[Respiratory reactions and afferent activity during various actions on the receptors of a transplanted reinnervated kidney].[对移植后重新神经支配的肾脏的感受器进行各种操作时的呼吸反应和传入活动]
Fiziol Zh SSSR Im I M Sechenova. 1974 Apr;60(4):613-23.

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Physiol Rev. 2015 Jan;95(1):83-123. doi: 10.1152/physrev.00025.2013.
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Extra sensory perception: the role of Gpr receptors in the kidney.超感官知觉:Gpr受体在肾脏中的作用。
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